1976038-41-1
1976038-41-1
Chemical Structure
TP-008
- CAS No.: 1976038-41-1
- Formula:C20H15ClFN5O2
- Molecular Weight:411.82
IUPAC Name: 2-(1-(2-(5-chloro-2-fluorophenyl)-5-methylpyridin-4-yl)-2-oxo-1,2-dihydro-3H-imidazo[4,5-c]pyridin-3-yl)acetamide
InChIKey: LVEUPFUJRKZPEN-UHFFFAOYSA-N
SMILES: O=C(N)CN(C1=C2C=CN=C1)C(N2C3=CC(C4=CC(Cl)=CC=C4F)=NC=C3C)=O
Biological Activity: TP-008, a chemical probe, is a potent, selective and orally active (Activin-Like Kinase 5) ALK5 inhibitor with pIC50 and pEC50 values of 7.6 and 6.63, respectively. TGFβRI-IN-2 can produce observed cardiac toxicity in vivo at high dose[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
TP-008 | 99.42% | TP-008, a chemical probe, is a potent, selective and orally active (Activin-Like Kinase 5) ALK5 inhibitor with pIC50 and pEC50 values of 7.6 and 6.63, respectively. TGFβRI-IN-2 can produce observed cardiac toxicity in vivo at high dose. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
Keywords
