OXS007417
OXS007417 induces differentiation of acute myeloid leukemia cells (EC50 = 48 nM) in vitro and shows antitumor effects in vivo.
For research use only. We do not sell to patients.
- CAS No.: 2761147-94-6
- Formula: C20H14F3N3O
- Molecular Weight:369.34
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HL-60 | EC50 |
48 nM
Compound: 28; 0X5007417
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Induction of differentiation of human HL-60 cells assessed as increase in CD11b positive cells after 4 days by phycoerythrin/DAPI staining-based flow cytometric analysis
Induction of differentiation of human HL-60 cells assessed as increase in CD11b positive cells after 4 days by phycoerythrin/DAPI staining-based flow cytometric analysis
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[PMID: 34672555] |
| OCI-AML-3 | EC50 |
87 nM
Compound: 28; 0X5007417
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Induction of differentiation of human OCI-AML-3 cells assessed as increase in CD11b positive cells after 4 days by phycoerythrin/DAPI staining-based flow cytometric analysis
Induction of differentiation of human OCI-AML-3 cells assessed as increase in CD11b positive cells after 4 days by phycoerythrin/DAPI staining-based flow cytometric analysis
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[PMID: 34672555] |
| THP-1 | EC50 |
118 nM
Compound: 28; 0X5007417
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Induction of differentiation of human THP-1 cells assessed as increase in CD11b positive cells after 4 days by phycoerythrin/DAPI staining-based flow cytometric analysis
Induction of differentiation of human THP-1 cells assessed as increase in CD11b positive cells after 4 days by phycoerythrin/DAPI staining-based flow cytometric analysis
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[PMID: 34672555] |
Chemical Information
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CAS No. 2761147-94-6
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Molecular Weight 369.34
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Formula C20H14F3N3O
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SMILES
FC(F)OC(C=C1)=CC=C1N2C=NC3=CN=C(C4=C(C)C=C(F)C=C4)C=C32
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
OXS007417 Related Classifications
HY-139877 Related Classifications
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