2. Anti-infection
  3. Virus Protease SARS-CoV
  4. (M)-AVI-4773

(M)-AVI-4773 is an orally active, blood-brain barrier permeable coronaviruses MPro inhibitor with an IC50 of 2.5 nM aginst SARS-CoV-2 MPro. (M)-AVI-4773 produces a rapid onset antiviral effect in mouse models of MERS-CoV and SARS-CoV-2 infection.

For research use only. We do not sell to patients.

(M)-AVI-4773

(M)-AVI-4773 Chemical Structure

CAS No. : 3111610-68-2

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(M)-AVI-4773 Related Antibodies

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Description

(M)-AVI-4773 is an orally active, blood-brain barrier permeable coronaviruses MPro inhibitor with an IC50 of 2.5 nM aginst SARS-CoV-2 MPro. (M)-AVI-4773 produces a rapid onset antiviral effect in mouse models of MERS-CoV and SARS-CoV-2 infection[1].

IC50 & Target

IC50: 2.5 nM aginst SARS-CoV-2 MPro[1]
Molecular Weight

444.39

Formula

C23H14F2N6O2
CAS No.
SMILES

FC1=CC(N=N2)=C(C=C1F)N2C3=C(C)N(CC#C)C(N(C4=CN=CC5=C4C=CC=C5)C3=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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(M)-AVI-4773 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(M)-AVI-47733111610-68-2Virus ProteaseSARS-CoVSARS coronavirusMERS-CoV SARS-CoV-2 antiviralInhibitorinhibitorinhibit

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