(M)-AVI-4773
(M)-AVI-4773 is an orally active, blood-brain barrier permeable coronaviruses MPro inhibitor with an IC50 of 2.5 nM aginst SARS-CoV-2 MPro. (M)-AVI-4773 produces a rapid onset antiviral effect in mouse models of MERS-CoV and SARS-CoV-2 infection.
For research use only. We do not sell to patients.
- CAS No.: 3111610-68-2
- Formula: C23H14F2N6O2
- Molecular Weight:444.39
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
IC50: 2.5 nM aginst SARS-CoV-2 MPro[1]
Chemical Information
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CAS No. 3111610-68-2
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Molecular Weight 444.39
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Formula C23H14F2N6O2
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SMILES
FC1=CC(N=N2)=C(C=C1F)N2C3=C(C)N(CC#C)C(N(C4=CN=CC5=C4C=CC=C5)C3=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(M)-AVI-4773 Related Classifications
HY-181033 Related Classifications
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