1. Recombinant Proteins
  2. Activin A Protein, Human/Mouse/Rat (HEK293)

Activin A Protein, Human/Mouse/Rat (HEK293)

Cat. No.: HY-P70311
Handling Instructions

Activin A Protein, Human/Mouse/Rat (HEK293) is a recombinant protein produced by HEK293 cells. Activin A, a multifunctional cytokine, is a member of transforming growth factor β (TGF β) superfamily. It is associated with a variety of pathophysiological processes, including inflammation, fibrosis, and tumorigenesis[1].

For research use only. We do not sell to patients.

Protein Expression Service

Recombinant Proteins-MedChemExpress
Size Price Stock Quantity
10 μg $170 In-stock
Estimated Time of Arrival: December 31
50 μg $510 In-stock
Estimated Time of Arrival: December 31
100 μg   Get quote  
250 μg   Get quote  

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  • Technical Parameters

  • Properties

  • Documentation

rHuActivin A; Inhibin beta A chain; INHBA; Activin A



HEK 293


P08476 (G310-S426)

Gene ID


Molecular Weight

Approximately 15.0 kDa

AA Sequence



Greater than 95% as determined by reducing SDS-PAGE.

Biological Activity
The ability to induce SMAD signaling in 293-Activin A Res cells has an ED50 value of 1.3 ng/mL.

Lyophilized powder.


Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Endotoxin Level

<1 EU/μg, determined by LAL method.


It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O or PBS.

Storage & Stability

Stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.


Room temperature in continental US;may vary elsewhere.


Activin A is expressed widely in various tissues and cells with strong bioactivities and is the mostly studied activin. It first binds to the type II activin receptors (ActIIRA or ActRIIB) on the member surface, and then recruits and phosphorylates type I activin receptors (ActRI). The phosphorylated ActRI activates Smad2 and Smad3, which form a complex with Smad4 to translocate to the nucleus. Activin and TGF-β share the same signaling pathway at the level of Smad2/3/4. Activin A exerts a variety of biological functions including regulation of hematopoietic cell proliferation, neuron differentiation, pituitary hormone secretion, and tissue repair. It is also involved in the process of many diseases, for example, inflammation, fibrosis and tumorigenesis[1].

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Activin A Protein, Human/Mouse/Rat (HEK293)
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