17 Results for "

Aesculus

" in MedChemExpress (MCE) Product Catalog:
Products (17)

17 Results for "Aesculus" in MCE Product Catalog:

3
Escin
Escin
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3 Cited Publications
Cat. No.: HY-B2114
CAS No.: 6805-41-0
Category:  

Triterpenes Hippocastanaceae Terpenoids Aesculus hippocastanum Plants Saccharides

Target:  

Apoptosis

Escin, a natural compound of triterpenoid saponins that can be isolated from horse chestnut (Aesculus hippocastanum) seeds, can be used as a vasoprotective anti-inflammatory, anti-edematous and anti-nociceptive agent .
2
Sodium aescinate
Sodium aescinate
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2 Cited Publications
Cat. No.: HY-N1404
CAS No.: 20977-05-3
Category:  

Triterpenes Hippocastanaceae Terpenoids Aesculus hippocastanum Plants Disease Research Fields Inflammation/Immunology

Target:  

NF-κB

Sodium aescinate is a triterpene saponin derived from Aesculus hippocastanum seeds, with anti-inflammatory and antioxidant activities . Sodium aescinate inhibits hepatocellular carcinoma growth by targeting CARMA3/NF-κB pathway .
1
Escin IA
Escin IA
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1 Cited Publications
Cat. No.: HY-N0554
CAS No.: 123748-68-5
Category:  

Infection Triterpenes other families Hippocastanaceae Terpenoids Aesculus hippocastanum Plants Disease Research Fields Cancer

Target:  

HIV Protease Monoamine Oxidase

Escin IA is an oral LOXL2 inhibitor and EMT inhibitor, with selectivity for LOXL2-expressing cells. Escin IA suppresses invasion, migration, and metastasis of breast cancer cells, and acts as the primary anti-TNBC metastasis constituent of Aesculus chinensis Bunge fruit saponin fraction. Escin IA can be used for the research of triple-negative breast cancer, acute inflammation, and ethanol-induced gastric mucosal lesions .
Isoescin IA
Isoescin IA
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Cat. No.: HY-N0556
CAS No.: 219944-39-5
Category:  

Infection Aesculus chinensis Bunge Other Terpenoids Hippocastanaceae Terpenoids Plants Disease Research Fields

Target:  

HIV Protease

Isoescin IA is a triterpenoid saponin isolated from the seeds of Aesculus chinensis. Isoescin IA has anti-HIV-1 protease activity .
Escin IB
Escin IB
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Cat. No.: HY-N0555
CAS No.: 26339-90-2
Category:  

Triterpenes Hippocastanaceae Terpenoids Aesculus hippocastanum Metabolic Disease Plants Disease Research Fields

Target:  

Lipase

Escin IB is a saponin isolated from skin and the endosperm of seeds of horse chestnut (Aesculus hippocastanum). Escin IB shows inhibitory effect on pancreatic lipase activity .
Isoescin IA (Standard)
Isoescin IA (Standard)
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Cat. No.: HY-N0556R
CAS No.: 219944-39-5
Category:  

Aesculus chinensis Bunge Other Terpenoids Hippocastanaceae Terpenoids Plants

Target:  

Reference Standards HIV Protease

Isoescin IA (Standard) is the analytical standard of Isoescin IA. This product is intended for research and analytical applications. Isoescin IA is a triterpenoid saponin isolated from the seeds of Aesculus chinensis. Isoescin IA has anti-HIV-1 protease activity .
Escin IA (Standard)
Escin IA (Standard)
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Cat. No.: HY-N0554R
CAS No.: 123748-68-5
Category:  

Triterpenes other families Hippocastanaceae Terpenoids Aesculus hippocastanum Plants

Target:  

Reference Standards HIV Protease

Escin IA (Standard) is the analytical standard of Escin IA. This product is intended for research and analytical applications. Escin IA is a triterpene saponin isolated from Aesculus hippocastanum, which inhibits HIV-1 protease with IC50 values of 35 μM. Escin IA has anti-TNBC metastasis activity, and its action mechanisms involved inhibition of epithelial-mesenchymal transition process by down-regulating LOXL2 expression .
21-Angeloyl-protoaescigenin
21-Angeloyl-protoaescigenin
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Cat. No.: HY-N13115
CAS No.: 35931-54-5
Synonyms: (Z)-Protoescigenin 21-tiglate
Category:  

Aesculus chinensis Bunge Triterpenes Hippocastanaceae Terpenoids Plants

Target:  

Others

21-Angeloyl-protoaescigenin (compound 11) is a glycosidic oleanane-type triterpenoid (BAT) that can be isolated from the acid hydrolysis product (AHP) of the crude extract of Aesculus chinensis seeds. Aesculus-derived triterpenoids (BAT) generally exhibit good antitumor, anti-inflammatory, and anti-Alzheimer's activities. Protoescigenin 21-tiglate has antitumor activity, with IC50 values of 38.2 μM and 33 μM against MCF-7 and HeLa cells, respectively .
Protoescigenin 21-tiglate
Protoescigenin 21-tiglate
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Cat. No.: HY-N13115A
CAS No.: 7047-43-0
Synonyms: (E)-21-Angeloyl-protoaescigenin
Category:  

Aesculus chinensis Bunge Triterpenes Hippocastanaceae Terpenoids Plants

Target:  

Others

Protoescigenin 21-tiglate (compound 10) is a glycosidic oleanane-type triterpenoid (BAT) that can be isolated from the acid hydrolysis product (AHP) of the crude extract of Aesculus chinensis seeds. Aesculus-derived triterpenoids (BAT) generally exhibit good antitumor, anti-inflammatory, and anti-Alzheimer's activities. However, the antitumor activity of Protoescigenin 21-tiglate is relatively weak, with IC50 values of >80 μM and 80 μM against MCF-7 and HeLa cells, respectively .
Escin IIa
Escin IIa
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Cat. No.: HY-107248
CAS No.: 158732-55-9
Category:  

Triterpenes other families Hippocastanaceae Terpenoids Aesculus hippocastanum Plants Disease Research Fields Inflammation/Immunology

Target:  

Others

Escin IIa, isolated from horse chestnut, the seeds of Aesculus hippocastanum L., has positive effects on acute inflammation in animals. Escin IIa has gastroprotections on ethanol-induced gastric mucosal lesions in rats .
Escin IIb
Escin IIb
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Cat. No.: HY-107247
CAS No.: 158800-83-0
Category:  

Triterpenes Hippocastanaceae Terpenoids Aesculus hippocastanum Plants Disease Research Fields Inflammation/Immunology

Target:  

Others

Escin IIb, isolated from horse chestnut, the seeds of Aesculus hippocastanum L., has positive effects on acute inflammation in animals . Escin IIb showed potent protective effects against ethanol-induced gastric mucosal lesions .
Deacetylescin Ia
Deacetylescin Ia
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Cat. No.: HY-N13082
CAS No.: 254896-53-2
Category:  

Aesculus chinensis Bunge Triterpenes Hippocastanaceae Terpenoids Plants

Target:  

Others

Deacetylescin Ia (compound 12) is a deacetylated compound with anti-hyperglycemic effects that can be extracted from the debittered Aesculus and deacetylated at the C-22 position. Deacetylescin Ia (100 mg/kg) can inhibit blood glucose elevation in mouse glucose tolerance tests .
Escin IB (Standard)
Escin IB (Standard)
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Cat. No.: HY-N0555R
CAS No.: 26339-90-2
Category:  

Triterpenes Hippocastanaceae Terpenoids Aesculus hippocastanum Plants

Target:  

Lipase Reference Standards

Escin IB (Standard) is the analytical standard of Escin IB. This product is intended for research and analytical applications. Escin IB is a saponin isolated from skin and the endosperm of seeds of horse chestnut (Aesculus hippocastanum). Escin IB shows inhibitory effect on pancreatic lipase activity .
Aesculinoside C
Aesculinoside C
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Cat. No.: HY-N17243
Category:  

Aesculus chinensis Bunge Hippocastanaceae Terpenoids Plants Pentacyclic Triterpenoids

Target:  

Others

Aesculinoside C is an acylated polyhydroxy oleanane-type triterpene saponin that is found in the seeds of Aesculus chinensis .
Aesculuside B
Aesculuside B
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Cat. No.: HY-N7303
CAS No.: 26339-92-4
Category:  

Tetracyclic Triterpenoids Hippocastanaceae Terpenoids Plants

Target:  

Drug Derivative

Aesculuside B is a natural product that can be found in Aesculus chinensis?Bunge.
Aescigenin
Aescigenin
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Cat. No.: HY-179335
CAS No.: 17806-68-7
Category:  

Aesculus chinensis Bunge Hippocastanaceae Terpenoids Plants Pentacyclic Triterpenoids

Target:  

Others

Aescigenin is a triterpenoid saponin compound that can be found in Aesculus hippocastanum. Aescigenin is the main component of sodium β-aescin, a compound that has the functions of reducing tissue edema, improving microcirculation, and anti-inflammation. It can be used in research on Bell's palsy .
Aesculioside B
Aesculioside B
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Cat. No.: HY-N16846
CAS No.: 106310-33-2
Category:  

Aesculus chinensis Bunge Triterpenes Hippocastanaceae Terpenoids Plants

Target:  

Drug Derivative

Aesculioside B is a natural triterpene.
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