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Anti-inflammatory agent 115

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-183367
    Anti-inflammatory agent 115

    		TNF Receptor Interleukin Related Inflammation/Immunology
    Anti-inflammatory agent 115 is a potent anti-inflammatory agent. Anti-inflammatory agent 115 reduces secretion of myeloperoxidase (MPO), TNF-α, IL-1β, and IL-6. Anti-inflammatory agent 115 decreases ear tissue thickness and neutrophil infiltration in 12-O-tetradecanoylphorbol-13-acetate (TPA) (HY-18739)-induced topical edema in mice. Anti-inflammatory agent 115 can be used for the research of inflammatory diseases .
    Anti-inflammatory agent 115
  • HY-150002
    Antibacterial agent 115

    		Bacterial Infection Inflammation/Immunology
    Antibacterial agent 115 (Compound 10) is an orally active antibacterial and anti-inflammatory agent .
    Antibacterial agent 115
  • HY-182939
    MNK1/2-IN-10

    		MNK Eukaryotic Initiation Factor (eIF) NF-κB Inflammation/Immunology
    MNK1/2-IN-10 is an orally active, selective MNK1/MNK2 inhibitor, with an IC50 of 10.84 nM for MNK1 and an IC50 of 12.81 nM for MNK2. MNK1/2-IN-10 inhibits eIF4E phosphorylation, the NF-κB signaling pathway, macrophage polarization, oxidative stress and the production of pro-inflammatory cytokines. MNK1/2-IN-10 alleviates kidney and spleen damage in LPS (HY-D1056)-induced inflammatory mouse models. Anti-inflammatory agent 115 is applicable for research related to acute inflammation .
    MNK1/2-IN-10

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