1. Anti-infection
  2. Bacterial
  3. Antibacterial agent 115

Antibacterial agent 115 

Cat. No.: HY-150002
Handling Instructions

Antibacterial agent 115 (Compound 10) is an orally active antibacterial and anti-inflammatory agent.

For research use only. We do not sell to patients.

Antibacterial agent 115 Chemical Structure

Antibacterial agent 115 Chemical Structure

CAS No. : 2259732-60-8

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Description

Antibacterial agent 115 (Compound 10) is an orally active antibacterial and anti-inflammatory agent[1].

In Vitro

Antibacterial agent 115 (Compound 10) shows antibacterial activity with MIC values of both 2.72 μg/mL against Staphylococcus aureussubsp.aureus (ATCC 29213), Staphylococcus epidermidis (ATCC 12228) and Staphylococcus aureus (ATCC 6538)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Antibacterial agent 115 (Compound 10) (0-40 mg/kg; i.g.; seven consecutive days) shows anti-inflammatory activity[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Kunming female mice (body weight 18–22 g), 12-O-tetradecylphorbol-13- acetate (TPA) induced ear edema mice model[1].
Dosage: 10, 20, 40 mg/kg
Administration: Gavage, seven consecutive days
Result: Inhibited swelling of mouse ears and inhibited the expression of TNF-α, IL-1β and p65.
Molecular Weight

544.77

Formula

C35H48N2O3

CAS No.
SMILES

C[[email protected]]12[[email protected]@](CC=C3[[email protected]]2(CC[[email protected]@]4([[email protected]@]3([H])C[[email protected]](C)(CC4)C(O)=O)C)C)([H])[[email protected]@]5([[email protected]@](C(C)(C(/C(C5)=C\C6=NC=CN=C6)=O)C)([H])CC1)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Antibacterial agent 115
Cat. No.:
HY-150002
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