3 Results for "

Bezold-Jarisch reflex

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "Bezold-Jarisch reflex" in MCE Product Catalog:

Cat. No.: HY-106909A
CAS No.: 153608-99-2
Synonyms: KAE-393
Target:  

5-HT Receptor

Research Areas:  

Cardiovascular Disease

YM114 (KAE-393) is a highly potent and selective (5-HT)3-receptor antagonist that does not affect Veratridine (HY-N6691)- or electrical stimulation-induced bradycardia in anesthetized rats. YM114 inhibits 2-methyl-5-HT (HY-19358)-induced Bezold-Jarisch reflex, which originates from (5-HT)3-receptor located on the endings of vagal afferent nerves in the heart .
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Cat. No.: HY-19136
CAS No.: 136013-69-9
Target:  

5-HT Receptor

Research Areas:  

Neurological Disease

WAY-100289 is an orally active antagonist for 5-HT3 receptor, that exhibits high affinity to the isolated rat vagus nerves with pA2 of 8.9. WAY-100289 inhibits the Bezold-Jarisch reflex in anesthetized and awake rats .
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Cat. No.: HY-182701
CAS No.: 149685-89-2
5-HT3 antagonist-7 (Compound 7e) is a competitive and selective 5-HT3 receptor antagonist. 5-HT3 antagonist-7 inhibits 5-HT-induced contractions in guinea pig ileum and guinea pig thoracic aorta. 5-HT3 antagonist-7 prevents 2-methyl-5-HT-induced vomiting episodes in ferrets .
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