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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
Cbl-b-IN-1
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "Cbl-b-IN-1" in MCE Product Catalog:
1
1 Cited Publications
Target:
Research Areas:
Cbl-b-IN-1 (Example 519) is an inhibitor of Cbl-b, with an IC50 of less than 100 nM. Cbl-b-IN-1 can promote the secretion of cytokines such as IL-2, IFN-γ, and TNF-α, facilitate T cell activation, and enhance the TCR signaling pathway. Cbl-b-IN-1 can be used in research on immunomodulation [1] .
Cat. No.: HY-159608
CAS No.: 3035210-39-7
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PROTAC Cbl-b-IN-1 (compound 64) is a potent Cbl-b PROTAC degrader with a DC50 of less than 30 nM. PROTAC Cbl-b-IN-1 can be used for cancer research [1].
Cat. No.: HY-159615
CAS No.: 2851878-87-8
Research Areas:
Cbl-b-IN-21 is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs). Cbl-b-IN-21 can be used for synthesis PROTAC Cbl-b-IN-1 (HY-159608) [1].
Cat. No.: HY-W797329
CAS No.: 2829898-76-0
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(3S)Lenalidomide-5-Br is a ligand for E3 ubiquitinase. (3S)Lenalidomide-5-Br can be used to synthesize PROTAC Cbl-b-IN-1 (HY-159608) [1].
Cat. No.: HY-159617
CAS No.: 3035215-25-6
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Cbz-Pip-2C-Pip-C-Pip is a PROTAC linker. Cbz-Pip-2C-Pip-C-Pip can be used for synthesis PROTAC Cbl-b-IN-1 (HY-159608) [1].
Cat. No.: HY-159618
Research Areas:
(3S)Lenalidomide-5-Pip-C-Pip-2C-Pip is an E3 Ligase Ligand-Linker Conjugate. (3S)Lenalidomide-5-Pip-C-Pip-2C-Pip can be used to synthesize PROTAC Cbl-b-IN-1 (HY-159608) [1].
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
