(3S)Lenalidomide-5-Br
Based on 1 Customer Validation
(3S)Lenalidomide-5-Br is a ligand for E3 ubiquitinase. (3S)Lenalidomide-5-Br can be used to synthesize PROTAC Cbl-b-IN-1 (HY-159608).
For research use only. We do not sell to patients.
- Purity: 98.61%
- CAS No.: 2829898-76-0
- Formula: C13H11BrN2O3
- Molecular Weight:323.15
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
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Cereblon |
Chemical Information
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CAS No. 2829898-76-0
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Appearance Solid
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Molecular Weight 323.15
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Formula C13H11BrN2O3
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Color Gray to gray purple
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SMILES
O=C1N([C@@H]2C(NC(CC2)=O)=O)CC3=CC(Br)=CC=C31
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (154.73 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.0945 mL | 15.4727 mL | 30.9454 mL | 77.3635 mL |
| 5 mM | 0.6189 mL | 3.0945 mL | 6.1891 mL | 15.4727 mL | |
| 10 mM | 0.3095 mL | 1.5473 mL | 3.0945 mL | 7.7363 mL | |
| 15 mM | 0.2063 mL | 1.0315 mL | 2.0630 mL | 5.1576 mL | |
| 20 mM | 0.1547 mL | 0.7736 mL | 1.5473 mL | 3.8682 mL | |
| 25 mM | 0.1238 mL | 0.6189 mL | 1.2378 mL | 3.0945 mL | |
| 30 mM | 0.1032 mL | 0.5158 mL | 1.0315 mL | 2.5788 mL | |
| 40 mM | 0.0774 mL | 0.3868 mL | 0.7736 mL | 1.9341 mL | |
| 50 mM | 0.0619 mL | 0.3095 mL | 0.6189 mL | 1.5473 mL | |
| 60 mM | 0.0516 mL | 0.2579 mL | 0.5158 mL | 1.2894 mL | |
| 80 mM | 0.0387 mL | 0.1934 mL | 0.3868 mL | 0.9670 mL | |
| 100 mM | 0.0309 mL | 0.1547 mL | 0.3095 mL | 0.7736 mL |