PROTAC Cbl-b-IN-1
PROTAC Cbl-b-IN-1 (compound 64) is a potent Cbl-b PROTAC degrader with a DC50 of less than 30 nM. PROTAC Cbl-b-IN-1 can be used for cancer research.
(Pink: Cbl-b ligand (HY-159615); Blue: Cereblon ligand (HY-W797329); Black: linker (HY-159617)).
For research use only. We do not sell to patients.
- CAS No.: 3035210-39-7
- Formula: C53H65F3N12O6
- Molecular Weight:1023.16
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Description
IC50 & Target
[1]|
Cereblon |
Cbl-b |
In Vitro
Cbl-b is an E3 ubiquitin-protein ligase, acting as a negative regulator of T cell activation. It can be utilized for studying diseases related to cell proliferation, particularly cancer.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS No. 3035210-39-7
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Molecular Weight 1023.16
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Formula C53H65F3N12O6
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SMILES
OC=O.FC(F)(C1=CC(CN2CCN(CC2)CCN3CCC(CC3)CN4CCN(C5=CC=C(C(N([C@@H]6C(NC(CC6)=O)=O)C7)=O)C7=C5)CC4)=CN8C1=CN(C9=CC([C@H](C%10=NN=CN%10C)C%11CCC%11)=CC=C9)C8=O)F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PROTAC Cbl-b-IN-1 Related Classifications
HY-159608 Related Classifications
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