1. Metabolic Enzyme/Protease
  2. E1/E2/E3 Enzyme
  3. Cbl-b-IN-1

Cbl-b-IN-1 

Cat. No.: HY-136339 Purity: 99.00%
Handling Instructions

Cbl-b-IN-1 (example 519) is a Cbl-b inhibitor, extracted from patent WO2019148005A1, with an IC50 <100 nM.

For research use only. We do not sell to patients.

Cbl-b-IN-1 Chemical Structure

Cbl-b-IN-1 Chemical Structure

CAS No. : 2368841-84-1

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 527 In-stock
Estimated Time of Arrival: December 31
5 mg USD 480 In-stock
Estimated Time of Arrival: December 31
10 mg USD 800 In-stock
Estimated Time of Arrival: December 31
25 mg USD 1550 In-stock
Estimated Time of Arrival: December 31
50 mg USD 2400 In-stock
Estimated Time of Arrival: December 31
100 mg USD 3600 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Cbl-b-IN-1 (example 519) is a Cbl-b inhibitor, extracted from patent WO2019148005A1, with an IC50 <100 nM[1].

IC50 & Target

IC50: <100 nM (Cbl-b)[1].

Molecular Weight

498.62

Formula

C₂₉H₃₄N₆O₂

CAS No.
SMILES

O=C(C1=NC(C2CC2)=CC(CN(CC3)CC43CC4)=C1)NC5=CC=CC(C6(CC7=NN=CN7C)COC6)=C5

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 60 mg/mL (120.33 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0055 mL 10.0277 mL 20.0554 mL
5 mM 0.4011 mL 2.0055 mL 4.0111 mL
10 mM 0.2006 mL 1.0028 mL 2.0055 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Cbl-b-IN-1E1/E2/E3 EnzymeE1 activating enzymeE2 conjugating enzymeE3 ligating enzymeUbiquitin activating enzymeUbiquitin conjugating enzymeUbiquitin ligaseInhibitorinhibitorinhibit

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Product Name:
Cbl-b-IN-1
Cat. No.:
HY-136339
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