5 Results for "

Cobra venom

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "Cobra venom" in MCE Product Catalog:

11
Cardiotoxin Analog (CTX) IV (6-12)
Cardiotoxin Analog (CTX) IV (6-12)
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11 Cited Publications
Referencia número: HY-P1902
No. CAS: 115722-23-1
Category:  

Cardiovascular Disease Natural Products Animals Disease Research Fields

Target:  

Apoptosis

Cardiotoxin Analog (CTX) IV (6-12) is a membrane active peptide that specifically targets negatively charged phospholipid membranes (such as phosphatidylserine and phosphatidylinositol). Cardiotoxin Analog (CTX) IV (6-12) was discovered in the venom of the Taiwan cobra. Cardiotoxin Analog (CTX) IV (6-12) is a chemically synthesized snake venom cardiotoxin that binds to cell membranes and embeds into lipid bilayers through hydrophobic interactions and electrostatic attraction, thereby destroying the stability of membrane structure. Cardiotoxin Analog (CTX) IV (6-12) can induce membrane lipid disorder and cell lysis, exhibiting hemolysis and cytotoxicity .
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11
Cardiotoxin Analog (CTX) IV (6-12) TFA
Cardiotoxin Analog (CTX) IV (6-12) TFA
0 Images
11 Cited Publications
Referencia número: HY-P1902A
No. CAS: 2918768-05-3
Category:  

Pyrrole Alkaloids Animals Other Diseases Disease Research Fields

Target:  

Apoptosis

Cardiotoxin Analog (CTX) IV (6-12) TFA is a membrane active peptide that specifically targets negatively charged phospholipid membranes (such as phosphatidylserine and phosphatidylinositol). Cardiotoxin Analog (CTX) IV (6-12) TFA was discovered in the venom of the Taiwan cobra. Cardiotoxin Analog (CTX) IV (6-12) TFA is a chemically synthesized snake venom cardiotoxin that binds to cell membranes and embeds into lipid bilayers through hydrophobic interactions and electrostatic attraction, thereby destroying the stability of membrane structure. Cardiotoxin Analog (CTX) IV (6-12) TFA can induce membrane lipid disorder and cell lysis, exhibiting hemolysis and cytotoxicity .
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Cobra Venom Factor
Cobra Venom Factor
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Referencia número: HY-NP004
Synonyms: CVF
Cobra Venom Factor (CVF) is a selective activator targeting complement components C3, C5, and factor B in the complement system. After binding to factor B, Cobra Venom Factor is cleaved by factor D, forming a stable C3/C5 convertase resistant to regulatory proteins H and I. This continuously hydrolyzes C3 and C5, depleting serum complement while inducing neutrophil migration, vascular leakage, and increased TNF-α levels. Cobra Venom Factor can be used to deplete complement and mimic complement activation-related pathological states, and is applied in animal models of complement-mediated diseases such as acute respiratory distress syndrome (ARDS), sepsis, and shock. Cobra Venom Factor can be isolated from the venom of cobras (e.g., Naja atra, Naja melanoleuca, Naja kaouthia, etc.) .
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OH-CATH
OH-CATH
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Referencia número: HY-P4071
Synonyms: Cathelicidin-OH antimicrobial peptide
Target:  

Bacterial

Áreas de investigación:  

Infection

OH-CATH is a natural antimicrobial peptide that can be isolated from the venom and tissue of Ophiophagus hannah (King Cobra) .
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PLA2-IN-1
PLA2-IN-1
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Referencia número: HY-173335
Target:  

Phospholipase

Áreas de investigación:  

Infection

PLA2-IN-1 (Compound 7) is a potent and selective inhibitor of phospholipase A2 (PLA2) with an IC50 value of 1 nM PLA2-IN-1 inhibits PLA2-induced coagulopathy in vitro. PLA2-IN-1 is promising for research of snakebite envenomation caused by cobra venom .
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