Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
DENV-IN-5
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "DENV-IN-5" in MCE Product Catalog:
Cat. No.: HY-143274
CAS No.: 2375781-06-7
Target:
Research Areas:
DENV-IN-5 (Compound 4b) is a dengue virus (DENV) inhibitor with EC50s of 1.47, 9.23, 7.08 and 8.91 μM against DENV-I ∼ IV replication, respectively. DENV-IN-5 also inhibits HIV-1IIIB strain with an EC50 of 0.1512 μM .
Cat. No.: HY-165430
CAS No.: 25111-96-0
Target:
Research Areas:
Antiviral agent 67 (compound PC6) is an inhibitor of DENV NS5 (RNA-dependent RNA polymerase) with a Ki value of 1.12 nM
Cat. No.: HY-134991
CAS No.: 55968-37-1
Synonyms: 3′-DeoxyguanosINe 5′-triphosphate
Research Areas:
3'-Deoxy-GTP (3′-Deoxyguanosine 5′-triphosphate), an analog of GTP, is a RNA chain terminator and suppresses RNA synthesis. 3'-Deoxy-GTP inhibits DENV NS5 RdRp (IC50: 0.02 μM) .
Cat. No.: HY-134991A
Synonyms: 3′-DeoxyguanosINe 5′-triphosphate trisodium
Research Areas:
3'-Deoxy-GTP (3′-Deoxyguanosine 5′-triphosphate) trisodium, an analog of GTP, is a RNA chain terminator and suppresses RNA synthesis. 3'-Deoxy-GTP trisodium inhibits DENV NS5 RdRp (IC50: 0.02 μM) .
Cat. No.: HY-187508
Target:
Research Areas:
JNJ-2594 is an inhibitor of dengue virus (DENV) NS5 RNA-dependent RNA polymerase (RdRP). JNJ-2594 inhibits the elongation activity of DENV2 and DENV3 NS5 polymerases with IC50 values of 5.8 μM and 3.2 μM, respectively, and inhibits de novo RNA synthesis of DENV2 with an IC50 of 23.5 μM. JNJ-2594 exhibits cross-inhibitory effects on human mitochondrial RNA polymerase. JNJ-2594 can be used in research on the discovery of dengue virus NS5 polymerase and DENV RdRP inhibitors .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
