3'-Deoxy-GTP
3'-Deoxy-GTP (3′-Deoxyguanosine 5′-triphosphate), an analog of GTP, is a RNA chain terminator and suppresses RNA synthesis. 3'-Deoxy-GTP inhibits DENV NS5 RdRp (IC50: 0.02 μM).
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- CAS. Nr.: 55968-37-1
- Formel: C10H16N5O13P3
- Molecular Weight:507.18
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Chemical Information
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CAS. Nr. 55968-37-1
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Molecular Weight 507.18
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Formel C10H16N5O13P3
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SMILES
O=C1C2=C(N([C@H]3[C@H](O)C[C@@H](COP(OP(OP(O)(O)=O)(O)=O)(O)=O)O3)C=N2)NC(N)=N1
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Synonyms
3′-Deoxyguanosine 5′-triphosphate
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Yin Z, et al. An adenosine nucleoside inhibitor of dengue virus. Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20435-9. [Content Brief]
[2]. Oliveira AF, et al. Potential Antivirals: Natural Products Targeting Replication Enzymes of Dengue and Chikungunya Viruses. Molecules. 2017 Mar 22;22(3):505. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
3'-Deoxy-GTP Related Classifications
HY-134991 Related Classifications
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