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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
56 Results for "
Disulfide bond
" in MedChemExpress (MCE) Product Catalog:
Products (56)
56 Results for "Disulfide bond" in MCE Product Catalog:
45
45 Publications Verification
Synonyms: DTT; rel-(2R,3R)-1,4-Dimercapto-2,3-butanediol
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6 Cited Publications
PACMA 31 is an irreversible, orally active protein disulfide isomerase (PDI) inhibitor with an IC50 of 10 μM. PACMA 31 forms a covalent bond with the active site cysteines of PDI. PACMA 31 shows tumor targeting ability and significantly suppresses ovarian tumor growth without causing toxicity to normal tissues . PACMA 31 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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2 Cited Publications
Cat. No.: HY-15917A
CAS No.: 16096-97-2
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1 Cited Publications
Cat. No.: HY-P4452
CAS No.: 209006-18-8
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CL2A is a claevable complicated PEG8- and triazole-containing PABC-peptide-mc linker. CL2A is cleavable through pH sensitivity, giving rise to bystander effect, and binds the antibody at a cysteine residue via a disulfide bond. Labetuzumab govitecan used this linker .
Cat. No.: HY-134633
CAS No.: 1808266-58-1
Synonyms: EV 06 chloride; UNR 844 chloride
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Alpha-lipoic acid choline ester (EV 06) chloride is choline ester of alpha-lipoic acid. Alpha-lipoic acid choline ester chloride reduces the disulfide bond level of lens proteins. Alpha-lipoic acid choline ester chloride improves lens elasticity. Alpha-lipoic acid choline ester chloride is hydrolyzed by ocular esterases to release alpha-lipoic acid and choline. Alpha-lipoic acid choline ester chloride is used for the research of presbyopia .
Cat. No.: HY-P5601
CAS No.: 214542-43-5
Cat. No.: HY-P5601A
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Tiopronin-cysteine disulfide is a soluble disulfide metabolite/derivative of Tiopronin (HY-B0373) formed by reaction of Tiopronin with cystine. Tiopronin-cysteine disulfide reduces cystine crystal formation in cystinuria. Tiopronin-cysteine disulfide can be used for the research of cystinuria .
Cat. No.: HY-P990059
CAS No.: 2760250-47-1
Synonyms: INT-016; AZD8205 Antibody
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Cat. No.: HY-W590681
CAS No.: 2803699-72-9
113-O12B is a disulfide bond-containing ionizable cationic lipidoid. 113-O12B can be used in that generation of lipid nanoparticles (LNPs) for the delivery of mRNA .
Cat. No.: HY-P3432
CAS No.: 2035480-78-3
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DM4-SMe is a metabolite of antibody-maytansin conjugates (AMCs) and a tubulin inhibitor, and also a cytotoxic moiety of antibody-drug conjugates (ADCs), which can be linked to antibody through disulfide bond or stable thioether bond. DM4-SMe inhibits KB cells with an IC50 of 0.026 nM. DM4-SMe is a highly toxic metabolite that can be oxidized and detoxified by human liver microsomes .
Cat. No.: HY-15917S2
CAS No.: 850153-85-4
Synonyms: DTT-d6
Cat. No.: HY-P4597
CAS No.: 62130-80-7
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Cat. No.: HY-P11035
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Cat. No.: HY-W096122
CAS No.: 142702-31-6
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DTSSP Crosslinker disodium is a protein cross-linker containing a disulfide bond. DTSSP Crosslinker disodium can react with sidechains of amino acids that are within close proximity .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
