Alpha-lipoic acid choline ester chloride
Based on 1 Customer Validation
Alpha-lipoic acid choline ester (EV 06) chloride is choline ester of alpha-lipoic acid. Alpha-lipoic acid choline ester chloride reduces the disulfide bond level of lens proteins. Alpha-lipoic acid choline ester chloride improves lens elasticity. Alpha-lipoic acid choline ester chloride is hydrolyzed by ocular esterases to release alpha-lipoic acid and choline. Alpha-lipoic acid choline ester chloride is used for the research of presbyopia.
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- Purity : 99.72%
- CAS No.: 1808266-58-1
- 화학식: C13H26ClNO2S2
- 분자량:327.93
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보관:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
Biological Activity
제품 설명
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:C57BL/6J (8-month-old)[1]
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Dosage:5% (formulated ophthalmic solution), 2.5 μL drop
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Administration:topical ocular; three times per day; 5 weeks
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Result:Exhibited increased elasticity compared to untreated contralateral eyes, with lower relative force required for equivalent Z displacements.
Was more elastic than lenses from 8-week-old (young) control mice in most cases.
Showed no significant crossover effect in untreated left eyes of treated mice.
Chemical Information
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CAS No. 1808266-58-1
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Appearance Solid
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분자량 327.93
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화학식 C13H26ClNO2S2
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Color Off-white to light yellow
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SMILES
O=C(OCC[N+](C)(C)C)CCCC[C@H]1SSCC1.[Cl-]
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Synonyms
EV 06 chloride; UNR 844 chloride
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선적
Room temperature in continental US; may vary elsewhere.
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보관
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
용액&용해도
In Vitro:
DMSO : 100 mg/mL (304.94 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (269 KB)
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SDS (597 KB)
- English - EN (597 KB)
- Français - FR (597 KB)
- Deutsch - DE (597 KB)
- Norwegian - NO (597 KB)
- Español - ES (597 KB)
- Swedish - SV (597 KB)
- Italian - IT (597 KB)
- Korean - KR (597 KB)
- Portuguese - PT (597 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.0494 mL | 15.2472 mL | 30.4943 mL | 76.2358 mL |
| 5 mM | 0.6099 mL | 3.0494 mL | 6.0989 mL | 15.2472 mL | |
| 10 mM | 0.3049 mL | 1.5247 mL | 3.0494 mL | 7.6236 mL | |
| 15 mM | 0.2033 mL | 1.0165 mL | 2.0330 mL | 5.0824 mL | |
| 20 mM | 0.1525 mL | 0.7624 mL | 1.5247 mL | 3.8118 mL | |
| 25 mM | 0.1220 mL | 0.6099 mL | 1.2198 mL | 3.0494 mL | |
| 30 mM | 0.1016 mL | 0.5082 mL | 1.0165 mL | 2.5412 mL | |
| 40 mM | 0.0762 mL | 0.3812 mL | 0.7624 mL | 1.9059 mL | |
| 50 mM | 0.0610 mL | 0.3049 mL | 0.6099 mL | 1.5247 mL | |
| 60 mM | 0.0508 mL | 0.2541 mL | 0.5082 mL | 1.2706 mL | |
| 80 mM | 0.0381 mL | 0.1906 mL | 0.3812 mL | 0.9529 mL | |
| 100 mM | 0.0305 mL | 0.1525 mL | 0.3049 mL | 0.7624 mL |
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