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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
EGFR-IN-9
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "EGFR-IN-9" in MCE Product Catalog:
Cat. No.: HY-161536
CAS No.: 2992670-33-2
Research Areas:
PROTAC EGFR degrader 9 (Compound C6) is an orally active CRBN-based PROTAC EGFR degrader. PROTAC EGFR degrader 9 exhibits a DC50 of 10.2 nM and a Kd of 240.2 nM against EGFR L858R/T790M/C797S. PROTAC EGFR degrader 9 exhibits potent degradation activity against various EGFR mutants, while sparing the EGFRWT. (Blue: CRBN ligand (HY-A0003), Black: linker (HY-161613); Pink: EGFR inhibitor (HY-161537)) .
Cat. No.: HY-161537
CAS No.: 2992670-44-5
EGFR ligand-9 is an EGFR ligand. EGFR ligand-9 can be used for synthesis of PROTAC EGFR degrader 9 (HY-161536) .
Cat. No.: HY-P990698
CAS No.: 2599198-83-9
Target:
Research Areas:
Cat. No.: HY-161613
CAS No.: 50733-91-0
Target:
Research Areas:
7-Bromoheptanoyl chloride is a linker of PROTAC EGFR degrader 9 (HY-161536) .
Cat. No.: HY-161538
CAS No.: 2580970-60-9
Research Areas:
Lenalidomide-C6-Br is a conjugate of E3 ligase ligand and linker. Lenalidomide-C6-Br can be utilized for synthesis of PROTAC EGFR degrader 9 (HY-161536) .
Cat. No.: HY-139884
CAS No.: 2765573-34-8
EGFR-IN-18 potently inhibits enzymatic activity in L858R/T790M/C797S mutant EGFR (4.9 nM), with a significantly lower activity for wild-type EGFR (47 nM).
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
