1226549-39-8
1226549-39-8
Chemical Structure
EGFR-IN-9
- CAS No.: 1226549-39-8
- Formula:C29H24N4O3
- Molecular Weight:476.53
IUPAC Name: (S)-N-(3-(4-((2-hydroxy-1-phenylethyl)amino)-6-phenylfuro[2,3-d]pyrimidin-5-yl)phenyl)acrylamide
InChIKey: GFTOODFOXIDLNF-HSZRJFAPSA-N
SMILES: C=CC(NC1=CC=CC(C2=C(C3=CC=CC=C3)OC4=NC=NC(N[C@@H](C5=CC=CC=C5)CO)=C42)=C1)=O
Biological Activity: EGFR-IN-9 (Compound 8) is a potent EGFR kinase inhibitor with IC50s of 7 nM, 28 nM for the wild type EGFR kinase and double mutant EGFR kinase (L858R/T790M). EGFR-IN-9 has antitumor activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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EGFR-IN-9 | 98.84% | EGFR-IN-9 (Compound 8) is a potent EGFR kinase inhibitor with IC50s of 7 nM, 28 nM for the wild type EGFR kinase and double mutant EGFR kinase (L858R/T790M). EGFR-IN-9 has antitumor activity. | ||||||||||||||||||||
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References
Keywords
