2765573-34-8
2765573-34-8
Chemical Structure
EGFR-IN-18
- CAS No.: 2765573-34-8
- Formula:C33H28N6O3S
- Molecular Weight:588.68
IUPAC Name: N-(3-(5-(2-acetamidopyridin-4-yl)-2-(methylthio)-1H-imidazol-4-yl)phenyl)-2-((1-oxoisoindolin-2-yl)methyl)benzamide
InChIKey: MYCFQBCOJLOXJZ-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=CC(C2=C(C3=CC(NC(C)=O)=NC=C3)NC(SC)=N2)=C1)C4=CC=CC=C4CN(CC5=C6C=CC=C5)C6=O
Biological Activity: EGFR-IN-18 potently inhibits enzymatic activity in L858R/T790M/C797S mutant EGFR (4.9 nM), with a significantly lower activity for wild-type EGFR (47 nM).
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
EGFR-IN-18 | EGFR-IN-18 potently inhibits enzymatic activity in L858R/T790M/C797S mutant EGFR (4.9 nM), with a significantly lower activity for wild-type EGFR (47 nM). | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
