2 Results for "

Gaultherin

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Gaultherin" in MCE Product Catalog:

Gaultherin
Gaultherin
0 Images
Cat. No.: HY-N1965
CAS No.: 490-67-5
Category:  

other families Ketones, Aldehydes, Acids Gaultheria yunnanensis Plants Ericaceae Disease Research Fields Inflammation/Immunology

Target:  

Free Radical Scavengers NF-κB p38 MAPK COX Monoamine Oxidase MMP Interleukin Related TNF Receptor Reactive Oxygen Species (ROS)

Gaultherin is an orally active non-steroidal anti-inflammatory agent. Gaultherin selectively inhibits NF-κB, MAPK, COX-2 (IC50 = 0.35 mg/mL), LOX (IC50 = 0.56 mg/mL) and HYAL (IC50 = 28.58 μg/mL) to exert anti-inflammatory, antipyretic and analgesic effects. Gaultherin exhibits modest direct antioxidant capacity, greater in cell-based models. Gaultherin does not affect COX-1 so that avoids the common gastrointestinal side effects of Aspirin (HY-14654) .
loading...
    loading...
View All Sizes
Gaultherin (Standard)
Gaultherin (Standard)
0 Images
Cat. No.: HY-N1965R
CAS No.: 490-67-5
Category:  

other families Ketones, Aldehydes, Acids Gaultheria yunnanensis Plants Ericaceae

Target:  

Reference Standards NF-κB p38 MAPK COX Reactive Oxygen Species (ROS) Monoamine Oxidase MMP Interleukin Related TNF Receptor

Gaultherin (Standard) is the analytical standard for Gaultherin (HY-N1965). Gaultherin is an orally active non-steroidal anti-inflammatory agent. Gaultherin selectively inhibits NF-κB, MAPK, COX-2 (IC50 = 0.35 mg/mL), LOX (IC50 = 0.56 mg/mL) and HYAL (IC50 = 28.58 μg/mL) to exert anti-inflammatory, antipyretic and analgesic effects. Gaultherin exhibits modest direct antioxidant capacity, greater in cell-based models. Gaultherin does not affect COX-1 so that avoids the common gastrointestinal side effects of Aspirin (HY-14654) .
loading...
    loading...
View All Sizes
Assay Types