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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
H22
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "H22" in MCE Product Catalog:
2
2 Cited Publications
Cat. No.: HY-P99136
Target:
Research Areas:
Cat. No.: HY-161141
CAS No.: 2761180-01-0
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EGFR/ C-Met-in-2 (Compound H-22) is a dual inhibitor of EGFR/c-Met. EGFR/c-Met-IN-2 inhibits cell proliferation by arresting G2/M phase. EGFR/c-Met-IN-2 has antitumor activity .
Cat. No.: HY-W040584
CAS No.: 492-98-8
1H,1'H-2,2'-Biimidazole is a metal-organic framework (MOF).
Cat. No.: HY-172108
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TGFβRI-IN-7 (compound 16W) is a potent inhibitor of TGFβRI. TGFβRI-IN-7 inhibits SMAD2/3 phosphorylation and H22 cell viability with IC50 values of 12 and 65 nM, respectively. TGFβRI-IN-7 shows anti-tumor efficacy in a xenograft model of H22 cells, with TGI of 79.6 % .
Cat. No.: HY-144232
CAS No.: 2768083-57-2
Anticancer agent 28 shows good antitumor activity in H22 allogeneic mice in vivo. Anticancer agent 28 has inhibitory potency in K562 cells of 50 times than oridonin, and its IC50 value is 0.09 μM.
Cat. No.: HY-139815
CAS No.: 1314556-93-8
ZYJ-34c is an orally active and potent histone deacetylase inhibitor (HDACi) with IC50s of 0.056 μM and 0.146 μM for HDAC6 and HDAC8, respectively. ZYJ-34c causes G1 phase arrest in low concentration. ZYJ-34c has antiproliferative activities. ZYJ-34c exhibits antitumor potency in MDA-MB-231 and HCT116 xenograft models and possesses antimetastatic potential in a mouse hepatoma-22 (H22) pulmonary metastasis model .
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Cat. No.: HY-182447
CAS No.: 69095-83-6
Synonyms: DL111-IT
Research Areas:
Contragestazol (DL111-IT) is a non-hormonal antifertility agent. Contragestazol reduces the expression of Cyclin D1 and CDK4, increases the expression of total retinoblastoma protein (pRb), and decreases the level of hyperphosphorylated pRb. Contragestazol induces G0/G1 phase cell cycle arrest. Contragestazol inhibits embryonic development by inducing luteal cell apoptosis and reducing intrauterine polyamine levels. Contragestazol exhibits antitumor activity against prostate cancer, S180 tumor and H22 tumor. Contragestazol shows extremely potent activity in terminating early pregnancy in animals .
Cat. No.: HY-W128191
CAS No.: 10087-64-6
Synonyms: 2,2'-Bipyrrole
1H,1'H-2,2'-Bipyrrole (2,2'-Bipyrrole) is a metal-organic framework (MOF).
Cat. No.: HY-W456336
CAS No.: 2413962-77-1
4,4'-(1H,1'H-[2,2'-Biimidazole]-1,1'-diyl)dibenzoic acid is a metal-organic framework (MOF).
Cat. No.: HY-W075088
CAS No.: 37572-50-2
Synonyms: 1,1'-Diaethyl-2,2'-biimidazol
1,1'-Diethyl-1H,1'H-2,2'-biimidazole (1,1'-Diaethyl-2,2'-biimidazol) is a metal-organic framework (MOF).
Cat. No.: HY-W112832
CAS No.: 1079311-38-8
Synonyms: 1,1-Bis(pyridin-4-ylmethyl)-2,2-bisimidazole
1,1'-Bis(pyridin-4-ylmethyl)-1H,1'h-2,2'-biimidazole (1,1-Bis(pyridin-4-ylmethyl)-2,2-bisimidazole) is a metal-organic framework (MOF).
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
