3-Carboxyphenylboronic acid
Based on 1 Customer Validation
3-Carboxyphenylboronic acid is a biochemical reagent with multiple functions including nanoparticle enhancement, perovskite passivation, fluorescence quenching, and adhesion. 3-Carboxyphenylboronic acid improves tumor penetration and pulmonary retention of nanoparticles, and serves as a tumor-targeting ligand for carboxymethyl chitosan nanoparticles. 3-Carboxyphenylboronic acid optimizes film crystallization via coordinate chelation of free lead/iodide ions in perovskites. 3-Carboxyphenylboronic acid acts as an additive for n-i-p perovskite solar cells. Conjugation of 3-Carboxyphenylboronic acid with PPEG8 quenches the near-infrared fluorescence of single-walled carbon nanotubes, enabling aqueous dispersion of carbon nanotubes through binding to the diol structure of saccharides.
For research use only. We do not sell to patients.
- Purity: 99.97%
- CAS No.: 25487-66-5
- Formula: C7H7BO4
- Molecular Weight:165.94
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
3-Carboxyphenylboronic acid modifies carboxymethyl chitosan nanoparticles (CB NPs), and the obtained CB NPs possess higher cellular uptake and Doxorubicin (HY-15142A) delivery efficiency within SH-SY5Y and H22 cells after 4 h incubation relative to unmodified nanoparticles; these modified nanoparticles display improved accumulation and penetration in SH-SY5Y multicellular spheroids and generate stronger proliferation suppression against the spheroids[1].
3-Carboxyphenylboronic acid optimizes the performance of ITO/SnO2/perovskite/spiro-OMeTAD/MoO3/Ag n-i-p perovskite films and devices: it chelates free lead ions to passivate film defects, increases grain size, narrows grain boundaries, and reduces surface roughness to 23.92 nm to improve crystallinity; meanwhile, it regulates energy levels, narrows the band gap, enhances visible light absorption, reduces trap-mediated non-radiative recombination, elevates open-circuit voltage, short-circuit current density and fill factor, and improves the photoelectric conversion efficiency of devices[2].
3-Carboxyphenylboronic acid conjugated with eight-branched polyethylene glycol polymer realizes stable dispersion of single-walled carbon nanotubes (SWNTs), effectively quenches the near-infrared fluorescence of (9,4)-type SWNTs, and binds fructose to reduce the fluorescence intensity of ARS complex[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 25487-66-5
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Appearance Solid
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Molecular Weight 165.94
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Formula C7H7BO4
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Color White to off-white
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SMILES
O=C(O)C1=CC=CC(B(O)O)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 175 mg/mL (1054.60 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
References
[1]. Wang X, et al. 3-Carboxyphenylboronic acid-modified carboxymethyl chitosan nanoparticles for improved tumor targeting and inhibitory. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 2017 Apr;113:168-177. [Content Brief]
[3]. Mu B, et al. A structure-function relationship for the optical modulation of phenyl boronic acid-grafted, polyethylene glycol-wrapped single-walled carbon nanotubes. Journal of the American Chemical Society. 2012 Oct 24;134(42):17620-7. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 6.0263 mL | 30.1314 mL | 60.2627 mL | 150.6569 mL |
| 5 mM | 1.2053 mL | 6.0263 mL | 12.0525 mL | 30.1314 mL | |
| 10 mM | 0.6026 mL | 3.0131 mL | 6.0263 mL | 15.0657 mL | |
| 15 mM | 0.4018 mL | 2.0088 mL | 4.0175 mL | 10.0438 mL | |
| 20 mM | 0.3013 mL | 1.5066 mL | 3.0131 mL | 7.5328 mL | |
| 25 mM | 0.2411 mL | 1.2053 mL | 2.4105 mL | 6.0263 mL | |
| 30 mM | 0.2009 mL | 1.0044 mL | 2.0088 mL | 5.0219 mL | |
| 40 mM | 0.1507 mL | 0.7533 mL | 1.5066 mL | 3.7664 mL | |
| 50 mM | 0.1205 mL | 0.6026 mL | 1.2053 mL | 3.0131 mL | |
| 60 mM | 0.1004 mL | 0.5022 mL | 1.0044 mL | 2.5109 mL | |
| 80 mM | 0.0753 mL | 0.3766 mL | 0.7533 mL | 1.8832 mL | |
| 100 mM | 0.0603 mL | 0.3013 mL | 0.6026 mL | 1.5066 mL |
3-Carboxyphenylboronic acid Related Classifications
HY-Y0395 Related Classifications
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