1228447-26-4
Chemical Structure
ATWLPPRAANLLMAAS
- CAS No.: 1228447-26-4
- Formula:C76H123N21O20S
- Molecular Weight:1682.98
InChIKey: OBPVLTCNYHKVBL-LVAZLNDASA-N
SMILES: O=C(N1[C@@H](CCC1)C(N2[C@@H](CCC2)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(N[C@@H](C)C(N[C@@H](CC(N)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CCSC)C(N[C@@H](C)C(N[C@@H](C)C(N[C@@H](CO)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC(C)C)NC([C@@H](NC([C@H]([C@H](O)C)NC([C@@H](N)C)=O)=O)CC3=CNC4=CC=CC=C34)=O
Biological Activity: ATWLPPRAANLLMAAS is a chimeric peptide with anti-angiogenic and potent anti-tumor effects. ATWLPPRAANLLMAAS can inhibit the proliferation, viability, migration, and invasion of human hepatocellular carcinoma cells, and induce apoptosis.[1][2].
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ATWLPPRAANLLMAAS | ATWLPPRAANLLMAAS is a chimeric peptide with anti-angiogenic and potent anti-tumor effects. ATWLPPRAANLLMAAS can inhibit the proliferation, viability, migration, and invasion of human hepatocellular carcinoma cells, and induce apoptosis.. | |||||||||||||||||||||
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References
- [1]. Wu D, et al. Anti-tumor effects of a novel chimeric peptide on S180 and H22 xenografts bearing nude mice[J]. Peptides, 2010, 31(5): 850-864.
- [2]. Wu D, et al. Peptide V3 inhibits the growth of human hepatocellular carcinoma by inhibiting the Ras/Raf/MEK/ERK signaling pathway[J]. Journal of Cancer, 2019, 10(7): 1693. [Content Brief]
