Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
HSD17B13-IN-1
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "HSD17B13-IN-1" in MCE Product Catalog:
Cat. No.: HY-148926
CAS No.: 2770246-02-9
Target:
Research Areas:
HSD17B13-IN-1 (compound 2) is a ppotent inhibitor of hydroxysteroid 17?-dehydrogenase 13 (HSD17B13), with the IC50 of ＜ 0.1 μM? estradiol? as substrates. HSD17B13-IN-1? plays an important role in nonalcoholic fatty liver diseases (NAFLDs) including NASH (nonalcoholic steatohepatitis) .
Cat. No.: HY-W003696
CAS No.: 201940-08-1
Synonyms: Tert-butyl 5-bromo-1,3-dihydro-2H-isoINdole-2- carboxylate
Target:
Research Areas:
tert-Butyl 5-bromoisoindoline-2-carboxylate (Tert-butyl 5-bromo-1,3-dihydro-2H-isoindole-2- carboxylate) is a PROTAC Linker. tert-Butyl 5-bromoisoindoline-2-carboxylate can be used in synthesis PTOTAC HSD17B13 degrader 1 (HY-159651) .
Cat. No.: HY-159651
CAS No.: 3046195-01-8
PTOTAC HSD17B13 degrader 1 is a HSD17B13 PROTAC degrader with a DC50 of 0.11 nM. HSD17B13 is a liver lipid droplet-associated medium-chain dehydrogenase/retinol dehydrogenase. PTOTAC HSD17B13 degrader 1 can be used in liver cancer research .
Cat. No.: HY-172122
CAS No.: 3067566-36-0
Research Areas:
FXR/HSD17B13 modulator 1 (compound 6) is a potent modulator of FXR/HSD17B13. FXR/HSD17B13 modulator 1 plays an important roel in metabolic dysfunction-associated steatohepatitis (MASH) research .
Cat. No.: HY-159660
CAS No.: 2357114-13-5
Target:
Research Areas:
E3 ligase Ligand 31 is a ligand for E3 ubiquitinase. E3 ligase Ligand 31 can be used to synthesize PTOTAC HSD17B13 degrader 1 (HY-159651) .
Cat. No.: HY-159662
CAS No.: 3035000-69-9
Research Areas:
HSD17B13 degrader 2 is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs). HSD17B13 degrader 2 can be used for synthesis PTOTAC HSD17B13 degrader 1 (HY-159651) .
Cat. No.: HY-159661
Research Areas:
E3 Ligase Ligand-linker Conjugate 114 is an E3 ubiquitinase ligand + linker conjugate. E3 Ligase Ligand-linker Conjugate 114 can be used to synthesize PTOTAC HSD17B13 degrader 1 (HY-159651) .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
