FXR/HSD17B13 modulator 1
Based on 1 Customer Validation
FXR/HSD17B13 modulator 1 (compound 6) is a potent modulator of FXR/HSD17B13. FXR/HSD17B13 modulator 1 plays an important roel in metabolic dysfunction-associated steatohepatitis (MASH) research.
For research use only. We do not sell to patients.
- Purity: 96.64%
- CAS No.: 3067566-36-0
- Formula: C26H19Cl2NO4
- Molecular Weight:480.34
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
All 17β-HSD Isoforms
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Biological Activity
Chemical Information
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CAS No. 3067566-36-0
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Appearance Solid
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Molecular Weight 480.34
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Formula C26H19Cl2NO4
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Color White to off-white
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SMILES
O=C(O)C1=CC=C(C=C1)C2=CC=C(C=C2)OCC3=C(ON=C3C4=C(C=CC=C4Cl)Cl)C5CC5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 12.5 mg/mL (26.02 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0819 mL | 10.4093 mL | 20.8186 mL | 52.0465 mL |
| 5 mM | 0.4164 mL | 2.0819 mL | 4.1637 mL | 10.4093 mL | |
| 10 mM | 0.2082 mL | 1.0409 mL | 2.0819 mL | 5.2046 mL | |
| 15 mM | 0.1388 mL | 0.6940 mL | 1.3879 mL | 3.4698 mL | |
| 20 mM | 0.1041 mL | 0.5205 mL | 1.0409 mL | 2.6023 mL | |
| 25 mM | 0.0833 mL | 0.4164 mL | 0.8327 mL | 2.0819 mL |