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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
HY-13259
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "HY-13259" in MCE Product Catalog:
2185
2185 Publications Verification
Synonyms: Z-Leu-Leu-Leu-al; MG132
Target:
Research Areas:
MG-132 (Z-Leu-Leu-Leu-al) is a potent proteasome and calpain inhibitor with IC50s of 100 nM and 1.2 μM, respectively. MG-132 effectively blocks the proteolytic activity of the 26S proteasome complex. MG-132, a peptide aldehyde, also is an autophagy activator. MG-132 also induces apoptosis .
18
18 Cited Publications
Synonyms: (S,R,S)-(-)-MG-132; Z-Leu-D-Leu-Leu-al
Target:
Research Areas:
(R)-MG-132 ((S,R,S)-(-)-MG-132) is the enantiomer of MG-132. (R)-MG-132 is a proteasome inhibitor with weaker cell cytotoxicity than MG-132 .
1
1 Cited Publications
Cat. No.: HY-13259D
Purity: ≥98.0%
Target:
Research Areas:
MG-132 (negative control) is the negative control form of MG-132 (HY-13259) .
Cat. No.: HY-13259G
CAS No.: 133407-82-6
Synonyms: Z-Leu-Leu-Leu-al (GMP)
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
