1. Metabolic Enzyme/Protease
  2. Proteasome
  3. (R)-MG-132

(R)-MG-132 

Cat. No.: HY-13259C Purity: >98.0%
Handling Instructions

(R)-MG-132 is the enantiomer of MG-132. (R)-MG-132 is a proteasome inhibitor with weaker cell cytotoxicity than MG-132.

For research use only. We do not sell to patients.

(R)-MG-132 Chemical Structure

(R)-MG-132 Chemical Structure

CAS No. : 1211877-36-9

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 188 In-stock
Estimated Time of Arrival: December 31
1 mg USD 50 In-stock
Estimated Time of Arrival: December 31
5 mg USD 180 In-stock
Estimated Time of Arrival: December 31
10 mg USD 320 In-stock
Estimated Time of Arrival: December 31
50 mg USD 980 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of (R)-MG-132:

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Description

(R)-MG-132 is the enantiomer of MG-132. (R)-MG-132 is a proteasome inhibitor with weaker cell cytotoxicity than MG-132[1].

IC50 & Target

Proteasome[1]

In Vitro

(R)-MG-132, the stereoisomer of MG-132, is studied as a potential inhibitor of chymotrypsin-like, trypsin-like, and peptidylglutamyl peptide hydrolyzing activities of proteasome[1].

Molecular Weight

475.62

Formula

C₂₆H₄₁N₃O₅

CAS No.

1211877-36-9

SMILES

CC(C)C[[email protected]](C(N)=O)N(C([[email protected]](CC(C)C)NC(OCC1=CC=CC=C1)=O)=O)[[email protected]](C=O)CC(C)C

Shipping

Room temperature in continental US; may vary elsewhere

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (210.25 mM)

H2O : < 0.1 mg/mL (insoluble)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1025 mL 10.5126 mL 21.0252 mL
5 mM 0.4205 mL 2.1025 mL 4.2050 mL
10 mM 0.2103 mL 1.0513 mL 2.1025 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 0.83 mg/mL (1.75 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 0.83 mg/mL (1.75 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Product Name:
(R)-MG-132
Cat. No.:
HY-13259C
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