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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
30 Results for "
KV11.1
" in MedChemExpress (MCE) Product Catalog:
Products (30)
30 Results for "KV11.1" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-P1280
CAS No.: 145808-47-5
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NS3623 is an activator of human ether-a-go-go-related gene (hERG1/KV11.1) potassium channels. NS3623 activates the IKr and Ito currents and has antiarrhythmic effect. NS3623 has a dual mode of action, being an inhibitor of hERG1 channels .
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CP 339818 hydrochloride is a non-peptide Kv1.3 channel (IC50 = 200 nM) and Kv1.4 channel blocker. CP 339818 hydrochloride inhibits HCN channel with IC50s of 18.9 μM and 43.4 μM against HCN1 and HCN4 (high Cl -). CP 339818 hydrochloride has significantly weaker blocking effects on Kv1.1, Kv1.2, Kv1.5, Kv1.6, Kv3.1-4, and Kv4.2 channels. CP 339818 hydrochloride selectively blocked Kv1.3, thereby inhibiting the activation process of human T cells. CP 339818 hydrochloride can be used to study the physiological functions of HCN and Kv channels .
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LUF7244 is a selective allosteric modulator of Kv11.1 channels. LUF7244 inhibits early afterdepolarizations. LUF7244 can be used for anti-arrhythmia research .
Cat. No.: HY-P3089A
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Cat. No.: HY-P3055A
Synonyms: DTX-I TFA
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Cat. No.: HY-120375
CAS No.: 1821638-40-7
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LUF7346 is a potent Kv11.1 (hERG) channel negative allosteric modulator, with an IC50 of 35.6 ± 3.2 nM .
Cat. No.: HY-P2707
CAS No.: 74504-53-3
Synonyms: α-DTX
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Cat. No.: HY-P1440A
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Cat. No.: HY-P3055
CAS No.: 107950-33-4
Synonyms: DTX-I
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VU0405601 is a potent KV11.1 channel activator. VU0405601 protects cardiac tissue from dofetilide (HY-B0232)-induced ventricular tachycardia .
Cat. No.: HY-126106
CAS No.: 622011-16-9
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(BrMT)2 (compound 2) is a non-peptide snail toxin that slows down the activation of Kv1.1 channels .
Cat. No.: HY-RS07184
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KCNV2 Human Pre-designed siRNA Set A contains three designed siRNAs for KCNV2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P3089
CAS No.: 119128-61-9
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Cat. No.: HY-P5788
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A-935142 is a human ether-a-go-go-related gene (hERG, Kv 11.1) channel activator. A-935142 enhances hERG current in a complex manner by facilitation of activation, reduction of inactivation, and slowing of deactivation, and abbreviates atrial and ventricular repolarization .
Cat. No.: HY-P5853
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Cat. No.: HY-P3014
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Cat. No.: HY-RS07126
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KCNH2 Human Pre-designed siRNA Set A contains three designed siRNAs for KCNH2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P5771
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
