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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
17 Results for "
LPCAT
" in MedChemExpress (MCE) Product Catalog:
Products (17)
17 Results for "LPCAT" in MCE Product Catalog:
Cat. No.: HY-W140439
CAS No.: 19420-56-5
Synonyms: 18:1 Lyso PC
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1-Oleoyl-sn-glycero-3-phosphocholine (18:1 Lyso PC), a lysophospholipid, is a GPR82 inhibitor. 1-Oleoyl-sn-glycero-3-phosphocholine abrogates constitutive Gi-coupled GPR82 activity, shifts active/inactive equilibrium to inactive, suppresses Gi protein activation, increases cAMP production, and decreases GTPγS binding to Gαi proteins. 1-Oleoyl-sn-glycero-3-phosphocholine contributes to adipocyte lipolysis regulation.1-Oleoyl-sn-glycero-3-phosphocholine exhibits reduced serum levels in mouse models of steatohepatitis, linked to hepatic Lpcat 1-4 up-regulation .
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(R)-HTS-3 is an lysophosphatidylcholine acyltransferase 3 (LPCAT3) inhibitor, with an IC50 of 0.09 μM. (R)-HTS-3 suppresses the C20:4 content of PE, PC, and PS, while promoting a correspondingelevation in C22:4 phospholipids and a paradoxical increase in C20:4 phosphatidylinositol (PI) lipids .
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TSI-01 is a selective LPCAT2 inhibitor, with IC50 values of 0.47 μM and 3.02 μM against LPCAT2 and LPCAT1, respectively. TSI-01 competitively inhibits acetyl-CoA (acetyl-CoA) targeting the lysophosphatidic acid acetyltransferase activity of LPCAT2, and suppresses PAF biosynthesis in calcium ionophore-stimulated mouse peritoneal macrophages. TSI-01 inhibits the proliferation of endometrial cancer cells and promotes endometrial cancer cell apoptosis (apoptosis). TSI-01 can be used for the research of endometrial cancer and PAF-related inflammatory diseases .
Cat. No.: HY-RS08194
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MBOAT2 Human Pre-designed siRNA Set A contains three designed siRNAs for MBOAT2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS18199
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Lpcat1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Lpcat1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS07764
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LPCAT1 Human Pre-designed siRNA Set A contains three designed siRNAs for LPCAT1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS07766
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LPCAT3 Human Pre-designed siRNA Set A contains three designed siRNAs for LPCAT3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS07765
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LPCAT2 Human Pre-designed siRNA Set A contains three designed siRNAs for LPCAT2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS07767
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LPCAT4 Human Pre-designed siRNA Set A contains three designed siRNAs for LPCAT4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24675
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Lpcat1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Lpcat1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS19065
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Lpcat3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Lpcat3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-E70259
CAS No.: 1246304-39-1
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18:2 (n6) Coenzyme A triammonium is a Coenzyme A. 18:2 (n6) Coenzyme A triammonium can be used to determine the effects of lysophospholipid acyltransferase activities in adipocyte differentiation .
Cat. No.: HY-RS25555
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Lpcat3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Lpcat3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P81530A
Synonyms: AYTL2; LPCAT; AGPAT9; PFAAP3; AGPAT10; LPCAT-1; lysoPAFAT
Cat. No.: HY-158790A
CAS No.: 2771208-82-1
Research Areas:
(S)-HTS-3 is a Lysophosphatidylcholine acyltransferase 3 (LPCAT3/MBOAT5) inhibitor with a human IC50 of 4.1 μM. (S)-HTS-3 inhibits the acyltransferase activity of LPCAT3. (S)-HTS-3 modestly reduces incorporation of deuterated arachidonic acid into C20:4 phosphatidylserine in myeloid leukemia cells .
Cat. No.: HY-P86947
Synonyms: 1-acylglycerophosphocholine O-acyltransferase antibody; 1-acylglycerophosphoserine O-acyltransferase antibody; LPCAT antibody; LPCAT3 antibody; LPLAT 5 antibody; LPSAT antibody; Lyso-PC acyltransferase 3 antibody; Lyso-PC acyltransferase antibody; Lyso-PS acyltransferase antibody; Lysophosphatidylcholine acyltransferase 3 antibody; 1-acylglycerophosphocholine O-acyltransferase antibody; 1-acylglycerophosphoserine O-acyltransferase antibody; LPCAT antibody; LPCAT3 antibody; LPLAT 5 antibody; LPSAT antibody; Lyso-PC acyltransferase 3 antibody; Lyso-PC acyltransferase antibody; Lyso-PS acyltransferase antibody; Lysophosphatidylcholine acyltransferase 3 antibody; Lysophosphatidylcholine acyltransferase antibody; Lysophosphatidylserine acyltransferase antibody; Lysophospholipid acyltransferase 5 antibody; MBOA5 antibody; MBOA5_HUMAN antibody; Membrane-bound O-acyltransferase domain-containing protein 5 antibody; O-acyltransferase domain-containing protein 5 antibody;
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
