2771208-82-1
2771208-82-1
Chemical Structure
(S)-HTS-3
- CAS No.: 2771208-82-1
- Formula:C17H18F2N2O
- Molecular Weight:304.33
InChIKey: SDNDFXUSMLLOMH-MRXNPFEDSA-N
SMILES: O=C(C1=CC(F)=CC(F)=C1)NC[C@H](C2=CC=CC=C2)N(C)C
Biological Activity: (S)-HTS-3 is a Lysophosphatidylcholine acyltransferase 3 (LPCAT3/MBOAT5) inhibitor with a human IC50 of 4.1 μM. (S)-HTS-3 inhibits the acyltransferase activity of LPCAT3. (S)-HTS-3 modestly reduces incorporation of deuterated arachidonic acid into C20:4 phosphatidylserine in myeloid leukemia cells[1].
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(S)-HTS-3 | (S)-HTS-3 is a Lysophosphatidylcholine acyltransferase 3 (LPCAT3/MBOAT5) inhibitor with a human IC50 of 4.1 μM. (S)-HTS-3 inhibits the acyltransferase activity of LPCAT3. (S)-HTS-3 modestly reduces incorporation of deuterated arachidonic acid into C20:4 phosphatidylserine in myeloid leukemia cells. | |||||||||||||||||||||
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References
Keywords
