3 Results for "

LY-AMC

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "LY-AMC" in MCE Product Catalog:

2
Tamarixetin
Tamarixetin
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2 Cited Publications
Cat. No.: HY-N1181
CAS No.: 603-61-2
Synonyms: 4'-O-Methyl Quercetin
Category:  

Flavonols Tamarix chinensis Lour. Plants Endogenous metabolite Tamaricaceae Flavonoids Phenols Polyphenols Disease Research Fields Inflammation/Immunology

Target:  

Endogenous Metabolite ClpP Bacterial Apoptosis Akt Interleukin Related COX JNK p38 MAPK Reactive Oxygen Species (ROS)

Tamarixetin (4'-O-Methyl Quercetin) is an orally active natural flavonoid derivative of quercetin and caseinolytic protease p (ClpP) inhibitor with anti-inflammatory, antioxidant and antitumor effects. Tamarixetin inhibits the hydrolytic activity of ClpP to the fluorescent substrate Suc-LY-AMC with an IC50 of 49.73 μM, which can be used for the study of Staphylococcus aureus infection. Tamarixetin inhibits tumor cell growth, induces apoptosis, and cell cycle arrest. Tamarixetin prevents cardiac hypertrophy by inhibiting the NFAT and AKT pathways .
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ClpP modulator-1
ClpP modulator-1
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Cat. No.: HY-175597
CAS No.: 2363753-48-2
Target:  

ClpP

Research Areas:  

Infection

ClpP modulator-1 (Compound BC8a), a peptidomimetic, is an allosteric ClpP modulator. ClpP modulator-1 is a ClpP activator at low concentration with EC50s of 0.35 and 0.58  μM for for Neisseria meningitides ClpP (NmClpP) and Escherichia coli ClpP (EcClpP), resepectively. ClpP modulator-1 also inhibits peptidase activity at high concentration by competitively inhibiting substrate protein (LY-AMC) binding to ClpP C sites. ClpP modulator-1 has antibacterial activity. ClpP modulator-1 can be used for bacterial infections research .
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Tamarixetin (Standard)
Tamarixetin (Standard)
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Cat. No.: HY-N1181R
CAS No.: 603-61-2
Synonyms: 4'-O-Methyl Quercetin (Standard)
Category:  

Flavonols Tamaricaceae Flavonoids Tamarix chinensis Lour. Phenols Polyphenols Plants Endogenous metabolite

Target:  

Reference Standards Endogenous Metabolite ClpP Bacterial Apoptosis Akt Interleukin Related COX JNK p38 MAPK Reactive Oxygen Species (ROS)

Tamarixetin (Standard) is the analytical standard of Tamarixetin. This product is intended for research and analytical applications. Tamarixetin (4'-O-Methyl Quercetin) is an orally active natural flavonoid derivative of quercetin and caseinolytic protease p (ClpP) inhibitor with anti-inflammatory, antioxidant and antitumor effects. Tamarixetin inhibits the hydrolytic activity of ClpP to the fluorescent substrate Suc-LY-AMC with an IC50 of 49.73 μM, which can be used for the study of Staphylococcus aureus infection. Tamarixetin inhibits tumor cell growth, induces apoptosis, and cell cycle arrest. Tamarixetin prevents cardiac hypertrophy by inhibiting the NFAT and AKT pathways .
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