670 Results for "

Lipid nanoparticle

" in MedChemExpress (MCE) Product Catalog:
Products (670)

670 Results for "Lipid nanoparticle" in MCE Product Catalog:

50
SM-102
SM-102
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50 Publications Verification
Cat. No.: HY-134541
CAS No.: 2089251-47-6
Purity:  99.97%
SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines .
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44
ALC-0315
ALC-0315
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44 Cited Publications
Cat. No.: HY-138170
CAS No.: 2036272-55-4
Purity:  99.81%
ALC-0315 is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine .
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26
mPEG2000-DMG
mPEG2000-DMG
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26 Cited Publications
Cat. No.: HY-112764
CAS No.: 160743-62-4
Purity:  98.40%
mPEG2000-DMG is used for the preparation of liposome for siRNA delivery with improved transfection efficiency in vitro. mPEG2000-DMG is also used for the lipid nanoparticle for an oral plasmid DNA delivery approach in vivo through a facile surface modification to improve the mucus permeability and delivery efficiency of the nanoparticles .
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21
DSPC
DSPC
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21 Cited Publications
Cat. No.: HY-W040193
CAS No.: 816-94-4
Synonyms: 1,2-Distearoyl-sn-glycero-3-PC; 1,2-Distearoyl-sn-glycero-3-phosphorylcholine
DSPC (1,2-Distearoyl-sn-glycero-3-phosphorylcholine) is a cylindrical-shaped lipid. DSPC is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system .
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20
C12-200
C12-200
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20 Cited Publications
Cat. No.: HY-145405
CAS No.: 1220890-25-4
Purity:  99.91%
C12-200 is a type of ionizable cationic lipid and helper lipid commonly used for mRNA delivery. In the hemophilia B mouse model, mRNA encoding human erythropoietin (EPO) and coagulation factor IX (FIX) can be successfully delivered and expressed using C12-200. C12-200 is utilized in research related to hemophilia B .
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9
DLin-KC2-DMA
DLin-KC2-DMA
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9 Cited Publications
Cat. No.: HY-112758
CAS No.: 1190197-97-7
Purity:  99.88%
DLin-KC2-DMA is an ionisable cationic lipid (pKa≈6) that is virtually non-toxic to antigen presenting cells (APCs). DLin-KC2-DMA produces significant siRNA-mediated gene silencing of GAPDH, when binds to lipid nanoparticles (LNP). DLin-KC2-DMA can be used in siRNA delivery studies .
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5
CKK-E12
CKK-E12
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5 Cited Publications
Cat. No.: HY-134781
CAS No.: 1432494-65-9
Purity:  ≥98.0%
CKK-E12 is a ionizable lipid in combination with other lipids make up the lipid nanoparticles which are used to deliver RNA-based research. CKK-E12 is highly selective toward liver parenchymal cell in vivo,
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3
DSPE-PEG2000-NHS
DSPE-PEG2000-NHS
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3 Cited Publications
Cat. No.: HY-W441014
DSPE-PEG2000-NHS is a PEG-modified phospholipid derivative that can be used to prepare liposomes. DSPE-PEG2000-NHS is commonly employed as a linker molecule for the surface modification of liposomes to confer targeting capabilities. DSPE-PEG2000-NHS can be used in the study of drug delivery .
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3
Polyvinyl alcohol (Mw 31000-50000, 87-89% hydrolyzed)
Polyvinyl alcohol (Mw 31000-50000, 87-89% hydrolyzed)
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3 Cited Publications
Cat. No.: HY-Y0850O
CAS No.: 9002-89-5
Synonyms: PVA (Mw 31000-50000, 87-89% hydrolyzed); Poly(Ethenol) (Mw 31000-50000, 87-89% hydrolyzed)
Polyvinyl alcohol (PVA; Poly (Ethenol)) (Mw 31000-50000, 87-89% hydrolyzed) is a polymer with emulsifying and stabilizing properties, with a degree of hydrolysis of 87-89%. Polyvinyl alcohol (Mw 31000-50000, 87-89% hydrolyzed) mainly acts as a stabilizer in the preparation of nanomedicines; it not only maintains the structural integrity of PEGylated PLGA nanoparticles during double emulsion synthesis, but also facilitates the preparation of chitosan/matrine-PLGA nanoparticle aqueous solutions and lipid-polymer nanoparticles. Polyvinyl alcohol (Mw 31000-50000, 87-89% hydrolyzed) can be widely used in research related to fields such as breast cancer .
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2
FTT5
FTT5
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2 Cited Publications
Cat. No.: HY-145793
CAS No.: 2328129-27-5
Purity:  ≥98.0%
FTT5 is an ionizable lipid that can be used to prepare lipid nanoparticles for efficient delivery of long-chain mRNA in vivo .
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2
DSPE-PEG(2000) Succinyl ammonium
DSPE-PEG(2000) Succinyl ammonium
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2 Cited Publications
Cat. No.: HY-N15971
CAS No.: 1445723-73-8
Category:  

Lipids

Target:  

Liposome

DSPE-PEG(2000) Succinyl ammonium is functionalized PEG lipid that can be used to synthesize lipid nanoparticles for drug delivery.
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2
306-O12B
306-O12B
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2 Cited Publications
Cat. No.: HY-W590532
CAS No.: 2566523-06-4
306-O12B is an ionizable cationic lipid used to prepare lipid nanoparticles (LNPs) for the delivery of mRNA .
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2
G0-C14
G0-C14
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2 Cited Publications
Cat. No.: HY-152229
CAS No.: 1510653-27-6
Purity:  ≥98.0%
G0-C14 is a cationic lipid-like compound alkyl-modified polyamidoamine (PAMAM) dendrimer. G0-C14 involves in the preparation of a series of macrophage-targeted nanoparticles (NPs). NPs can be used for agent and vaccine delivery .
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2
NT1-O14B
NT1-O14B
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2 Cited Publications
Cat. No.: HY-137500
CAS No.: 2739805-64-0
Purity:  98.43%
NT1-O14B is a tryptamine-derived lipidoid. NT1-O14B incorporates NT-lipidoid into BBB-impermeable lipid nanoparticles (LNPs), enabling the LNPs to cross the BBB. NT1-O14B enhances brain delivery via intravenous injection. NT1-O14B can be used in ischemic stroke research .
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1
DSPE-PEG-Amine, MW 2000 ammonium
DSPE-PEG-Amine, MW 2000 ammonium
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1 Cited Publications
Cat. No.: HY-125924
CAS No.: 474922-26-4
Purity:  99.96%
Synonyms: DSPE-PEG-NH2, MW 2000 ammonium; DSPE-PEG(2000) Amine ammonium
DSPE-PEG-Amine, MW 2000 (ammonium), an amine derivative of phospholipid poly ethylene glycol, is used in the synthesis of solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents .
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1
306Oi10
306Oi10
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1 Cited Publications
Cat. No.: HY-151507
CAS No.: 2322290-93-5
Purity:  ≥98.0%
306Oi10 is a branched ionizable lipid that can be used to construct lipid nanoparticles (LNPs) for delivering messenger RNA. The surface ionization of lipid nanoparticles is related to the effectiveness of mRNA delivery. The tail of 306Oi10 has a one-carbon branch, which provides it with stronger surface ionization compared to lipids with linear tails, thereby enhancing its mRNA delivery efficacy. 306Oi10 can be used in research related to mRNA delivery .
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1
Firefly luciferase mRNA-LNP
Firefly luciferase mRNA-LNP
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1 Cited Publications
Cat. No.: HY-153229
Firefly luciferase mRNA-LNP is a lipid nanoparticle (LNP) containing firefly luciferase mRNA. Firefly luciferase mRNA-LNP exhibits a stable nanostructure, in which LNP plays a key role in effectively protecting and transporting mRNA to cells. Luciferase is a bioluminescent reporter gene for gene regulation and functional studies. Firefly Luciferase mRNA-LNP expresses firefly luciferase protein after entering the cells, which is often used for promoter activity detection or dual fluorescent molecular complementation experiments. Firefly luciferase mRNA-LNP is studied in research for RNA delivery, cell viability, and translation efficiency .
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1
Lipid 10
Lipid 10
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1 Cited Publications
Cat. No.: HY-150115
CAS No.: 2430034-02-7
Purity:  ≥95.0%
Lipid 10 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
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1
4A3-Cit
4A3-Cit
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1 Cited Publications
Cat. No.: HY-153373
CAS No.: 2768211-13-6
4A3-Cit is an ionizable lipid used for the generation of lipid nanoparticles (LNPs).
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1
Ionizable lipid-1
Ionizable lipid-1
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1 Cited Publications
Cat. No.: HY-156630
CAS No.: 2055939-68-7
Purity:  ≥98.0%
Ionizable lipid-1 (compound II-10) is an ionizable lipid (pKa=6.16) that can be used to prepare lipid nanoparticles (LNP) with bilayer structure .
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