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Polyvinyl alcohol (Mw 31000-50000, 87-89% hydrolyzed)  (Synonyms: PVA (Mw 31000-50000, 87-89% hydrolyzed); Poly(Ethenol) (Mw 31000-50000, 87-89% hydrolyzed))

Cat. No.: HY-Y0850O Assay: 88.3%
Handling Instructions Technical Support

Polyvinyl alcohol (PVA; Poly (Ethenol)) (Mw 31000-50000, 87-89% hydrolyzed) is a polymer with emulsifying and stabilizing properties, with a degree of hydrolysis of 87-89%. Polyvinyl alcohol (Mw 31000-50000, 87-89% hydrolyzed) mainly acts as a stabilizer in the preparation of nanomedicines; it not only maintains the structural integrity of PEGylated PLGA nanoparticles during double emulsion synthesis, but also facilitates the preparation of chitosan/matrine-PLGA nanoparticle aqueous solutions and lipid-polymer nanoparticles. Polyvinyl alcohol (Mw 31000-50000, 87-89% hydrolyzed) can be widely used in research related to fields such as breast cancer.

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Polyvinyl alcohol (Mw 31000-50000, 87-89% hydrolyzed)

Polyvinyl alcohol (Mw 31000-50000, 87-89% hydrolyzed) 화학구조

CAS No. : 9002-89-5

사이즈 가격 재고 수량
10 g 해외재고보유
25 g 해외재고보유
50 g 해외재고보유
100 g 해외재고보유
> 100 g   견적 받기  

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고객리뷰

Based on 3 publication(s) in Google Scholar

Other Forms of Polyvinyl alcohol (Mw 31000-50000, 87-89% hydrolyzed):

Top Publications Citing Use of Products

3 Publications Citing Use of MCE Polyvinyl alcohol (Mw 31000-50000, 87-89% hydrolyzed)

  • Biological Activity

  • 순도&문서

  • References

  • 고객리뷰

제품 설명

Polyvinyl alcohol (PVA; Poly (Ethenol)) (Mw 31000-50000, 87-89% hydrolyzed) is a polymer with emulsifying and stabilizing properties, with a degree of hydrolysis of 87-89%. Polyvinyl alcohol (Mw 31000-50000, 87-89% hydrolyzed) mainly acts as a stabilizer in the preparation of nanomedicines; it not only maintains the structural integrity of PEGylated PLGA nanoparticles during double emulsion synthesis, but also facilitates the preparation of chitosan/matrine-PLGA nanoparticle aqueous solutions and lipid-polymer nanoparticles. Polyvinyl alcohol (Mw 31000-50000, 87-89% hydrolyzed) can be widely used in research related to fields such as breast cancer[1][2][3].

In Vitro

Polyvinyl alcohol (Mw 31000-50000, 87-89% hydrolyzed) (0.5% (w/w); overnight) acts as a stabilizer during double emulsion solvent evaporation to produce Dexamethasone (HY-14648)-loaded lipid-polymeric nanoparticles with a mean particle size of ~380.5 nm, polydispersity index of 0.233, and z-potential of -21.9 mV[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Polyvinyl alcohol (Mw 31000-50000, 87-89% hydrolyzed) (0.5% (w/v)) functions as an aqueous excipient for fabricating lipid-polymeric nanoparticles, with no direct pharmacodynamic effects observed in male C57BL/6 mice with cisplatin-induced sensorineural hearing loss[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

분자량

31000-50000 (Approximately)

화학식

(C2H4O)n

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CCC(O)C.[n]

선적

Room temperature in continental US; may vary elsewhere.

보관
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
용액&용해도
In Vitro: 

H2O : 20 mg/mL (ultrasonic and warming and heat to 60°C)

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
순도&문서

Purity: 88.3%

References
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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상품명:
Polyvinyl alcohol (Mw 31000-50000, 87-89% hydrolyzed)
Cat. No.:
HY-Y0850O
수량:
MCE Japan Authorized Agent: