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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
Long QT Syndrome
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "Long QT Syndrome" in MCE Product Catalog:
1
Target:
Research Areas:
Ibutilide (U70226E) fumarate, an action potential-prolonging antiarrhythmic, is a potent blocker of the rapidly activating delayed rectifier K + current (IKr) in AT-1 cells .
1
Target:
Research Areas:
Ibutilide (U70226E free base), an action potential-prolonging antiarrhythmic, is a potent blocker of the rapidly activating delayed rectifier K + current (IKr) in AT-1 cells .
1
1 Cited Publications
Cat. No.: HY-P1604
CAS No.: 60748-45-0
Target:
Research Areas:
1
1 Cited Publications
Cat. No.: HY-P1604A
Target:
Research Areas:
Cat. No.: HY-W516880
CAS No.: 73736-50-2
Synonyms: O-Demethylastemizole
Research Areas:
Desmethylastemizole (O-Demethylastemizole) , a metabolite of Astemizole (HY-12532), is a β-hematin (βH) inhibitor. Desmethylastemizole has an antiplasmodium activity against P. falciparum with IC50 of 0.12, 0.11 and 0.06 μM for Pf3D7, PfDd2, and PfItG strains, respectively. Desmethylastemizole is also a Histamine H1 receptor antagonist. Desmethylastemizole significantly blocks hERG K + channels and also inhibits histone-lysine N-methyltransferase EZH2 activity. Desmethylastemizole can be used for long QT syndrome and malaria research .
Target:
Research Areas:
AZSMO-23 is a potent hERG K + channel activator. AZSMO-23 activats WT hERG pre-pulse and tail current with EC50 values of 28.6, 11.2 µM, respectively. AZSMO-23 has the potential for the research of long QT syndrome .
Target:
Research Areas:
KCNQ1 activator-1 (compound 5) is a potent activator of KCNQ1 channel with an EC50 of 1.69 μM. KCNQ1 activator-1 has the potential for the research of long QT syndrome (LQTS) .
Cat. No.: HY-121520
CAS No.: 132850-40-9
Cat. No.: HY-P701834
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: KCNH2; HERG1; Prev. LQT2; Potassium Voltage-Gated Channel Subfamily H Eag-Related Member 2; HERG; Ether-A-Go-Go-Related Potassium Channel Protein; Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 2; Voltage-Gated Channel Subfamily H Member 2; Voltage-Gated Inwardly Rectifying Potassium Channel KCNH2; Human Ether-A-Go-Go-Related Gene; Ether-A-Go-Go-Related Gene Potassium Channel 1; Uncharacterized Protein KCNH2; Voltage-Gated Potassium Channel Subunit Kv11.1; Human Ether-A-Go-Go-Related; Kv11.1; Potassium Channel HERG1; Erg1; Potassium Channel HERG; Ether-A-Go-Go-Related Protein 1; KCNH2 Protein; Long QT Syndrome Type 2; HERG-1; Eag-Related Protein 1; SQT1; Eag Homolog; ERG1; ERG-1; ERG; H-ERG; Potassium Voltage-Gated Channel Subfamily H Member 2; Potassium Channel, Voltage Gated Eag Related Subfamily H, Member 2
Species:
Human
Source:
HEK293
Cat. No.: HY-P703937
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: KCNH2; HERG1; Prev. LQT2; Potassium Voltage-Gated Channel Subfamily H Eag-Related Member 2; HERG; Ether-A-Go-Go-Related Potassium Channel Protein; Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 2; Voltage-Gated Channel Subfamily H Member 2; Voltage-Gated Inwardly Rectifying Potassium Channel KCNH2; Human Ether-A-Go-Go-Related Gene; Ether-A-Go-Go-Related Gene Potassium Channel 1; Uncharacterized Protein KCNH2; Voltage-Gated Potassium Channel Subunit Kv11.1; Human Ether-A-Go-Go-Related; Kv11.1; Potassium Channel HERG1; Erg1; Potassium Channel HERG; Ether-A-Go-Go-Related Protein 1; KCNH2 Protein; Long QT Syndrome Type 2; HERG-1; Eag-Related Protein 1; SQT1; Eag Homolog; ERG1; ERG-1; ERG; H-ERG; Potassium Voltage-Gated Channel Subfamily H Member 2; Potassium Channel, Voltage Gated Eag Related Subfamily H, Member 2
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
