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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
107 Results for "
MC Receptor
" in MedChemExpress (MCE) Product Catalog:
Products (107)
107 Results for "MC Receptor" in MCE Product Catalog:
24
24 Publications Verification
Synonyms: α-Melanocyte-Stimulating Hormone
Target:
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology
24
24 Publications Verification
Cat. No.: HY-P0252A
CAS No.: 171869-93-5
Synonyms: α-Melanocyte-Stimulating Hormone TFA
Target:
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology
15
15 Cited Publications
Target:
Research Areas:
BQ-788 is a potent, selective ETB receptor antagonist with IC50 of 1.2 nM for inhibition of ET-1 binding to human Girardi heart cells, poorly inhibiting the binding to ETA receptors in human neuroblastoma cell line SK-N-MC cells with IC50 of 1300 nM .
4
4 Cited Publications
Cat. No.: HY-P2336A
Target:
Research Areas:
3
3 Cited Publications
Cat. No.: HY-P0227
CAS No.: 168482-23-3
Target:
Research Areas:
1
1 Cited Publications
Target:
Research Areas:
THIQ is the first selective agonist of the melanocortin-4 receptor (MC4R), with high affinity and potency for hMC4R (IC50=1.2 nM, EC50=2.1 nM) and rMC4R (IC50=0.6 nM, EC50=2.9 nM). THIQ maintains low potency at MC1R, MC3R and MC5R. THIQ plays a role in eliciting erectile activity in rodents. THIQ acts as a pharmacoperone of the MC4R rescuing the cell surface expression and signaling of some intracellularly retained MC4R mutants .
1
Target:
Research Areas:
Metabolic Disease Inflammation/Immunology Endocrinology Cancer
1
1 Cited Publications
Target:
Research Areas:
PF-07258669 is an orally active melanocortin-4 receptor (MC4R) antagonist that antagonizes MC4R with an IC50 of 13 nM (Ki=0.46 nM). PF-07258669 can be used for the research of cachexia, anorexia, or anorexia nervosa .
1
Target:
Research Areas:
1
Target:
Research Areas:
1
1 Cited Publications
Cat. No.: HY-P1215A
Target:
Research Areas:
1
1 Cited Publications
Cat. No.: HY-P1531
CAS No.: 72629-65-3
Target:
Research Areas:
1
1 Cited Publications
Cat. No.: HY-P1216A
Target:
Research Areas:
1
1 Cited Publications
Cat. No.: HY-N2466A
CAS No.: 1566590-77-9
Synonyms: MT-I acetate; [Nle4,D-Phe7]-α-MSH acetate
Target:
Research Areas:
Metabolic Disease Inflammation/Immunology Endocrinology Cancer
1
1 Cited Publications
Cat. No.: HY-P80062
Synonyms: LHR antibody;
BA-1 antibody;
CD 44 antibody;
CD44 antibody;
CD44 antigen antibody;
CD44 molecule (Indian blood group) antibody;
CD44 molecule antibody;
CD44_HUMAN antibody;
CDw44 antibody;
Cell surface glycoprotein CD44 antibody;
chondroitin sulfate proteoglycan 8 antibody;
CSPG8 antibody;
ECMR-III antibody;
Epican antibody;
Extracellular matrix Receptor III antibody;
GP90 lymphocyte homing/adhesion Receptor antibody;
HCELL antibody;
hematopoietic cell E- and L-selectin ligand antibody;
Heparan sulfate proteoglycan antibody;
Hermes antigen antibody;
homing function and Indian blood group system antibody;
HSA antibody;
HUTCH-I antibody;
HUTCH1 antibody;
Hyaluronate Receptor antibody;
IN antibody;
MC56 antibody;
MDU2 antibody;
MDU3 antibody
Synonyms: MT-7117
Target:
Research Areas:
Dersimelagon (MT-7117) is an orally active, selective melanocortin 1 receptor (MC1R) agonist with EC50 values of 8.16, 3.91, 1.14 and 0.251 nM for human (h), cynomolgus monkey (cm), mouse (m) and rat (r) MC1R, respectively. Dersimelagon shows good affinity for hMC1R and hMC4R with Ki values of 2.26, 32.9 nM, respectively. Dersimelagon can be used for the research of skin pigmentation .
Cat. No.: HY-P5971
CAS No.: 1456699-27-6
Synonyms: Mifomelatide
Target:
Research Areas:
Target:
Research Areas:
JNJ-10229570 is an antagonist of melanocortin receptor 1 (MC1R) and melanocortin receptor 5 (MC5R), which inhibits sebaceous gland differentiation and the production of sebum-specific lipids. JNJ-10229570 inhibits the binding of 125I-NDP-α-MSH to cells expressing human MC1R and MC5R, with IC50 values of 270 nM and 200 nM, respectively.
Cat. No.: HY-W002603
CAS No.: 31166-44-6
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
