3 Results for "

MPTP hydrochloride (Standard)

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "MPTP hydrochloride (Standard)" in MCE Product Catalog:

MPTP hydrochloride (Standard)
MPTP hydrochloride (Standard)
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Cat. No.: HY-15608R
CAS No.: 23007-85-4
Target:  

Reference Standards Dopamine Receptor Apoptosis

Research Areas:  

Neurological Disease Cancer

Iproniazid (phosphate) (Standard) is the analytical standard of Iproniazid (phosphate). This product is intended for research and analytical applications. Iproniazid phosphate is a non-selective, irreversible monoamine oxidase (MAO) inhibitor of the hydrazine class. Iproniazid phosphate has antidepressive activity .
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Docosahexaenoic acid (Standard)
Docosahexaenoic acid (Standard)
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Cat. No.: HY-B2167R
CAS No.: 6217-54-5
Synonyms: DHA (Standard); Cervonic acid (Standard)
Category:  

Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Disease markers Endogenous metabolite Cardiovascular System Disorder

Target:  

Reference Standards Endogenous Metabolite

Docosahexaenoic acid (Standard) is the analytical standard of Docosahexaenoic acid. This product is intended for research and analytical applications. Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. It can be obtained directly from fish oil and maternal milk. In Vitro: Docosahexaenoic acid (DHA) is essential for the growth and functional development of the brain in infants. DHA is also required for maintenance of normal brain function in adults. The inclusion of plentiful DHA in the diet improves learning ability and memory . DHA is an essential requirement in every step of brain development like neural cell proliferation, migration, differentiation, synaptogenesis. The multiple double bonds and unique structure allow DHA to impart special membrane characteristics for effective cell signaling. Many development disorders like dyslexia, autism spectrum disorder, attention deficit hyperactivity disorder, schizophrenia etc. are causally related to decreased level of DHA . DHA is a potent RXR ligand inducing robust RXR activation already at low micro molar concentrations. The EC50 for RXRα activation by DHA is about 5-10 μM fatty acid . In Vivo: Docosahexaenoic acid administration over 10 weeks significantly reduces the number of reference memory errors, without affecting the number of working memory errors, and significantly increases the docosahexaenoic acid content and the docosahexaenoic acid/arachidonic acid ratio in both the hippocampus and the cerebral cortex . DHA treatment exerts neuroprotective actions on an experimental mouse model of PD. There is a decrease tendency in brain lipid oxidation of MPTP mice but it does not significantly .
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ER-000444793 (Standard)
ER-000444793 (Standard)
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Cat. No.: HY-100852R
CAS No.: 792957-74-5
Target:  

Mitochondrial Metabolism Reference Standards

Research Areas:  

Cancer

ER-000444793 (Standard) is the analytical standard of ER-000444793 (HY-100852). This product is intended for research and analytical applications. ER-000444793 is a potent inhibitor of mitochondrial permeability transition pore (mPTP) opening. ER-000444793 inhibits mPTP with an IC50 of 2.8 μM.
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