19 Results for "

Mevalonic acid

" in MedChemExpress (MCE) Product Catalog:
Products (19)

19 Results for "Mevalonic acid" in MCE Product Catalog:

12
12 Publications Verification
Cat. No.: HY-113071A
CAS No.: 2618458-93-6
Purity:  ≥98.0%
Synonyms: MVA lithium salt
Mevalonic acid (MVA) lithium salt is a precursor substance of the mevalonate pathway, which is essential for cell growth and proliferation. Mevalonic acid lithium salt is effective in inhibiting Simvastatin (HY-17502)-induced decrease in C2C12 cell viability in vitro. Mevalonic acid lithium salt can be used in studies of myopathy and heart failure .
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1 Cited Publications
Cat. No.: HY-107855
CAS No.: 674-26-0
Purity:  99.15%
Synonyms: (±)-Mevalonolactone; Mevalolactone
DL-Mevalonolactone ((±)-Mevalonolactone;Mevalolactone) is the δ-lactone form of mevalonic acid, a precursor in the mevalonate pathway. DL-Mevalonolactone is orally active against HMGCR mutation and statin caused myopathy . DL-Mevalonolactone induces inflammation and oxidative stress response with decreased mitochondrial membrane potential (MMP) and induces mitochondrial swelling [2][4].
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Cat. No.: HY-N9474
CAS No.: 108869-00-7
Synonyms: 5-DiphosphoMevalonic acid tetralithium; Mevalonic acid 5-diphosphate tetralithium
Mevalonic acid 5-pyrophosphate (5-Diphosphomevalonic acid) tetralithium is an endogenous metabolite of the mevalonate pathway .
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Cat. No.: HY-113071
CAS No.: 150-97-0
Synonyms: MVA
Mevalonic acid (MVA) is a precursor substance of the mevalonate pathway, which is essential for cell growth and proliferation. Mevalonic acid is effective in inhibiting Simvastatin (HY-17502)-induced decrease in C2C12 cell viability in vitro. Mevalonic acid can be used in studies of myopathy and heart failure .
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Cat. No.: HY-143996S
CAS No.: 2747918-57-4
Purity:  ≥99.0%
Mevalonic acid- 13C,d3 (sodium) is the 13C- and deuterium labeled Mevalonic acid .
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Cat. No.: HY-135700
CAS No.: 19115-49-2
Purity:  ≥98.0%
Mevalonolactone is an intermediate metabolite in the eukaryotic mevalonate pathway, serving as the stable δ-lactone form of mevalonate with oral activity. Mevalonolactone exhibits binding affinity for ZNF384 (Ka = 12.6 μM) and inhibitory activity against aconitase (aconitase). Mevalonolactone promotes the nuclear localization of ZNF384 and enhances its binding to the GGPPS promoter. Mevalonolactone induces insulin resistance, disrupts glucose and lipid metabolism, enhances the isoprenylation of K-Ras, and inhibits the activation of the insulin signaling pathway. Mevalonolactone inhibits polypeptide synthesis of HMG-CoA reductase in isolated rat hepatocytes, promotes its degradation, and reduces its enzymatic activity. Mevalonolactone impairs mitochondrial function in rat brains. Mevalonolactone promotes the development of metabolically unhealthy obesity. Mevalonolactone can be used in research related to metabolically abnormal obesity, mevalonic aciduria, HMGCR-related limb-girdle myopathy, and statin-induced myopathy .
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Cat. No.: HY-107855S
CAS No.: 347840-19-1
Purity:  99.27%
Synonyms: (±)-Mevalonolactone-d7; Mevalolactone-d7
DL-Mevalonolactone-d7 is the deuterium labeled DL-Mevalonolactone. DL-Mevalonolactone ((±)-Mevalonolactone) is the δ-lactone form of mevalonic acid, a precursor in the mevalonate pathway. DL-Mevalonolactone (Mevalonolactone) decreases mitochondrial membrane potential (?Ψm), NAD(P)H content and the capacity to retain Ca2+ in the brain, besides inducing mitochondrial swelling .
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Cat. No.: HY-113071C
CAS No.: 32451-23-3
Synonyms: (S)-MVA
(S)-Mevalonic acid is the isomer of Mevalonic acid (HY-113071). Mevalonic acid ((S)-DCIT) is a precursor substance of the mevalonate pathway, which is essential for cell growth and proliferation. Mevalonic acid is effective in inhibiting Simvastatin (HY-17502)-induced decrease in C2C12 cell viability in vitro. Mevalonic acid can be used in studies of myopathy and heart failure .
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Cat. No.: HY-113071AR
CAS No.: 2618458-93-6
Synonyms: MVA lithium salt (Standard)
Mevalonic acid lithium salt (Standard) is the analytical standard of Mevalonic acid lithium salt. This product is intended for research and analytical applications. Mevalonic acid (MVA) lithium salt is a precursor substance of the mevalonate pathway, which is essential for cell growth and proliferation. Mevalonic acid lithium salt is effective in inhibiting Simvastatin (HY-17502)-induced decrease in C2C12 cell viability in vitro. Mevalonic acid lithium salt can be used in studies of myopathy and heart failure .
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Cat. No.: HY-W700346
CAS No.: 1215802-31-5
D,L-Mevalonic acid (dicyclohexylammonium) is a kind of biochemical reagent.
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Cat. No.: HY-126746
CAS No.: 4423-58-9
Target:  

Antibiotic

Corynecin I is an antibiotic produced by Corynebacterium hydrocarboclastus, and its precursor (D-(-) threo-p-amino phenyl serinol-N-acetylamine) has a minimal inhibitory effect on the synthesis of Corynecin from mevalonic acid .
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Cat. No.: HY-W725424
CAS No.: 96949-03-0
Synonyms: (R)-MVA sodium
Target:  

Drug Isomer

Research Areas:  

Others

(R) -Mevalonic acid ( (R) -MVA) sodium is an isomer of Mevalonic acid (HY-113071) . Mevalonic acid (MVA) is a precursor substance in the mevalonate pathway and is crucial for cell growth and proliferation.
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Cat. No.: HY-107855S1
CAS No.: 61219-76-9
Synonyms: (±)-Mevalonolactone-d3; Mevalolactone-d3
DL-Mevalonolactone-d3 is the deuterium labeled DL-Mevalonolactone . DL-Mevalonolactone ((±)-Mevalonolactone;Mevalolactone) is the δ-lactone form of mevalonic acid, a precursor in the mevalonate pathway. DL-Mevalonolactone (Mevalonolactone) decreases mitochondrial membrane potential ( Ψm), NAD(P)H content and the capacity to retain Ca2+ in the brain, besides inducing mitochondrial swelling .
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Cat. No.: HY-107855R
CAS No.: 674-26-0
Synonyms: (±)-Mevalonolactone (Standard); Mevalolactone (Standard)
DL-Mevalonolactone (Standard) is the analytical standard of DL-Mevalonolactone. This product is intended for research and analytical applications. DL-Mevalonolactone ((±)-Mevalonolactone;Mevalolactone) is the δ-lactone form of mevalonic acid, a precursor in the mevalonate pathway. DL-Mevalonolactone is orally active against HMGCR mutation and statin caused myopathy . DL-Mevalonolactone induces inflammation and oxidative stress response with decreased mitochondrial membrane potential (MMP) and induces mitochondrial swelling .
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Cat. No.: HY-N10619
CAS No.: 1164-45-0
Gibberellin A12 is a free C20-gibberellin, serving as a gibberellin biosynthesis intermediate and metabolite precursor. Gibberellin A12 exists in maturing Sechium edule seed testa, developing Pisum sativum seeds and Gibberella fujikuroi .
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Cat. No.: HY-N19716
CAS No.: 34427-31-1
Austamide is an indole alkaloid found in cultures of Aspergillus ustus. Austamide undergoes biosynthesis via the classical mevalonate pathway with nonface-selective reverse prenylation of its indole ring .
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Cat. No.: HY-107855S2
CAS No.: 53771-22-5
Synonyms: (±)-Mevalonolactone-13C; Mevalolactone-13C
DL-Mevalonolactone- 13C ((±)-Mevalonolactone- 13C) is the 13C-labeled DL-Mevalonolactone (HY-107855). DL-Mevalonolactone ((±)-Mevalonolactone;Mevalolactone) is the δ-lactone form of mevalonic acid, a precursor in the mevalonate pathway. DL-Mevalonolactone is orally active against HMGCR mutation and statin caused myopathy. DL-Mevalonolactone induces inflammation and oxidative stress response with decreased mitochondrial membrane potential (MMP) and induces mitochondrial swelling.
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Cat. No.: HY-107855S4
CAS No.: 287111-36-8
Synonyms: (±)-Mevalonolactone-13C2; Mevalolactone-13C2
DL-Mevalonolactone- 13C2 ((±)-Mevalonolactone- 13C2) is the 13C-labeled DL-Mevalonolactone (HY-107855). DL-Mevalonolactone ((±)-Mevalonolactone;Mevalolactone) is the δ-lactone form of mevalonic acid, a precursor in the mevalonate pathway. DL-Mevalonolactone is orally active against HMGCR mutation and statin caused myopathy . DL-Mevalonolactone induces inflammation and oxidative stress response with decreased mitochondrial membrane potential (MMP) and induces mitochondrial swelling [2][4].
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Cat. No.: HY-W752587
CAS No.: 349553-98-6
Synonyms: (±)-Mevalonolactone-d4; Mevalolactone-d4
DL-Mevalonolactone-d4 ( (±)-Mevalonolactone-d4) is the deuterium labeled DL-Mevalonolactone (HY-107855). DL-Mevalonolactone ((±)-Mevalonolactone;Mevalolactone) is the δ-lactone form of mevalonic acid, a precursor in the mevalonate pathway. DL-Mevalonolactone is orally active against HMGCR mutation and statin caused myopathy . DL-Mevalonolactone induces inflammation and oxidative stress response with decreased mitochondrial membrane potential (MMP) and induces mitochondrial swelling .
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