18 Results for "

NLS peptide

" in MedChemExpress (MCE) Product Catalog:
Products (18)

18 Results for "NLS peptide" in MCE Product Catalog:

Cat. No.: HY-P11662
CAS No.: 521076-75-5
Target:  

Peptides

Research Areas:  

Cancer

NLS peptide is a nuclear localization signal peptide, a short amino acid sequence that can be recognized by nuclear transport machinery (such as the Importin protein complex). NLS peptide can directionally transport the molecules or nanoparticles linked to it into the nucleus, and the N-terminal Cys terminus can be used for subsequent coupling. NLS peptide can be used to construct nucleus-specific imaging probes and nucleus-targeted nanoparticles
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1 Cited Publications
Cat. No.: HY-P2272A
Target:  

Wnt β-catenin

Research Areas:  

Cancer

NLS-StAx-h TFA is a selective, cell permeable, stapled peptide Wnt signaling inhibitor with an IC50 of 1.4 μM. NLS-StAx-h TFA efficiently inhibits β-catenin-transcription factor interactions. NLS-StAx-h TFA shows anti-proliferation of cancer cells .
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Cat. No.: HY-P1877A
Target:  

Peptides

Research Areas:  

Cancer

SV40 T-Ag-derived NLS peptide TFA is a nuclear localization signal DNA tagged to this peptide efficiently translocates into the cell nucleus .
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Cat. No.: HY-P1877
CAS No.: 105425-98-7
Target:  

Peptides

Research Areas:  

Cancer

SV40 T-Ag-derived NLS peptide is a nuclear localization signal DNA tagged to this peptide efficiently translocates into the cell nucleus .
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Cat. No.: HY-P10600A
Target:  

Ras

Research Areas:  

Others

BIMAX2 acetate is a high affinity nuclear localization signal (NLS) peptide. BIMAX2 acetate can mimic the activity of the classical nuclear localization signal (cNLS) and competitively bind to importin α, thereby inhibiting the binding of cNLS-cargo proteins to importin α. BIMAX2 acetate can be used to study the role of RBBP4 in regulating nuclear import efficiency and cell senescence .
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Cat. No.: HY-P11208C
Target:  

GABA Receptor

Research Areas:  

Inflammation/Immunology

mNLS-CPP-WSTF TFA is the trifluoroacetate salt of mNLS-CPP-WSTF (HY-P11208). mNLS-CPP-WSTF is a nuclear localization signal (NLS)-cell-penetrating peptide based on the mouse WSTF sequence. mNLS-CPP-WSTF significantly inhibits the GABARAP-WSTF interaction, WSTF degradation and inflammatory gene expression. mNLS-CPP-WSTF effectively attenuates chronic inflammation, liver fibrosis and cartilage damage in metabolic-dysfunction-associated steatohepatitis (MASH) and osteoarthritis (OA) mice model. mNLS-CPP-WSTF is promising for research of chronic inflammatory diseases such as MASH and OA .
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Cat. No.: HY-P11207
CAS No.: 1228086-59-6
Synonyms: NLS-cell penetrating peptide
Target:  

Peptides

Research Areas:  

Inflammation/Immunology

NLS-CPP is a nuclear localization signal (NLS)-cell-penetrating peptide, which contains the NLS of OCT6. NLS-CPP facilitates nuclear delivery. NLS-CPP can be used for chronic inflammatory diseases s research, such as metabolic-dysfunction-associated steatohepatitis (MASH) and osteoarthritis (OA) .
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Cat. No.: HY-P11208
Target:  

GABA Receptor

Research Areas:  

Inflammation/Immunology

mNLS-CPP-WSTF is a nuclear localization signal (NLS)-cell-penetrating peptide based on the mouse WSTF sequence. mNLS-CPP-WSTF significantly inhibits the GABARAP-WSTF interaction, WSTF degradation and inflammatory gene expression. mNLS-CPP-WSTF effectively attenuates chronic inflammation, liver fibrosis and cartilage damage in metabolic-dysfunction-associated steatohepatitis (MASH) and osteoarthritis (OA) mice model. mNLS-CPP-WSTF is promising for research of chronic inflammatory diseases such as MASH and OA .
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Cat. No.: HY-P2272
CAS No.: 2872559-21-0
Target:  

Wnt β-catenin

Research Areas:  

Cancer

NLS-StAx-h is a selective, cell permeable, stapled peptide Wnt signaling inhibitor with an IC50 of 1.4 μM. NLS-StAx-h efficiently inhibits β-catenin-transcription factor interactions. NLS-StAx-h shows anti-proliferation of cancer cells .
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Cat. No.: HY-P11076
Target:  

Complement System

Research Areas:  

Cancer

CP-EPS8-NLS is a peptide with anti-AML property. CP-EPS8-NLS interferes with EPS8-associated signaling and exerts anti-AML activity in various AML cell types. CP-EPS8-NLS has potent antitumor activity in xenograft tumor models. CP-EPS8-NLS downregulates EPS8 expression and its downstream pathway .
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Cat. No.: HY-P10600
CAS No.: 1105053-46-0
Target:  

Ras

Research Areas:  

Others

BIMAX2 is a high affinity nuclear localization signal (NLS) peptide. BIMAX2 can mimic the activity of the classical nuclear localization signal (cNLS) and competitively bind to importin α, thereby inhibiting the binding of cNLS-cargo proteins to importin α. BIMAX2 can be used to study the role of RBBP4 in regulating nuclear import efficiency and cell senescence .
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Cat. No.: HY-P3657A
Target:  

Fluorescent Dye

Research Areas:  

Cancer

Biotin-KKKRKV acetate is the biotinylated KKKRKV acetate. KKKRKV is a nuclear localization signal (NLS) peptide derived from simian virus 40 .
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Cat. No.: HY-172713
Target:  

Liposome

Research Areas:  

Infection

DSPE-PEG1000-MPG is a PEG compound which composed of DSPE and a peptide vector (MPG). MPG is derived from both the nuclear localisation sequence (NLS) of SV40 large T antigen and the fusion peptide domain of HIV-1 gp41. MPG could deliver short oligonucleotides into cells efficiently and independently of the endosomal pathway .
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Cat. No.: HY-172714A
Target:  

Liposome

Research Areas:  

Infection

DSPE-PEG3400-MPG is a PEG compound which composed of DSPE and a peptide vector (MPG). MPG is derived from both the nuclear localisation sequence (NLS) of SV40 large T antigen and the fusion peptide domain of HIV-1 gp41. MPG could deliver short oligonucleotides into cells efficiently and independently of the endosomal pathway .
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Cat. No.: HY-172715
Target:  

Liposome

Research Areas:  

Infection

DSPE-PEG5000-MPG is a PEG compound which composed of DSPE and a peptide vector (MPG). MPG is derived from both the nuclear localisation sequence (NLS) of SV40 large T antigen and the fusion peptide domain of HIV-1 gp41. MPG could deliver short oligonucleotides into cells efficiently and independently of the endosomal pathway .
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Cat. No.: HY-P1876D
CAS No.: 1818224-73-5
Target:  

Peptides

Research Areas:  

Others

Cys-NLS is a cysteine-containing nuclear localization signal peptide derived from the simian virus 40 large T antigen, which enhances nuclear import. Cys-NLS can undergo a coupling reaction through the common backbone of Cys .
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Cat. No.: HY-172714
Target:  

Liposome

Research Areas:  

Infection

DSPE-PEG2000-MPG is a PEG compound which composed of DSPE and a peptide vector (MPG). MPG is derived from both the nuclear localisation sequence (NLS) of SV40 large T antigen and the fusion peptide domain of HIV-1 gp41. MPG could deliver short oligonucleotides into cells efficiently and independently of the endosomal pathway .
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Cat. No.: HY-187486A
Synonyms: DOPE-PEG2000-Mal-Cys-MPG
Research Areas:  

Others

DOPE-PEG2000-MPG (DOPE-PEG2000-Mal-Cys-MPG) is an amphiphilic lipid-PEG-peptide conjugate consisting of DOPE (1,2-dioleoyl-sn-glycero-3-phosphoethanolamine), PEG2000, and the MPG peptide, a cell-penetrating peptide derived from the HIV-1 gp41 fusion peptide and the nuclear localization sequence (NLS) of SV40 large T antigen. DOPE-PEG2000-MPG is used for intracellular delivery of siRNA, DNA, and other macromolecules.
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