17 Results for "

NPC1L1

" in MedChemExpress (MCE) Product Catalog:
Products (17)

17 Results for "NPC1L1" in MCE Product Catalog:

16
16 Cited Publications
Cat. No.: HY-17376
CAS No.: 163222-33-1
Synonyms: SCH 58235
Target:  

Keap1-Nrf2 Autophagy

Research Areas:  

Cardiovascular Disease Cancer

Ezetimibe (SCH 58235) is a potent cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator.
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1
1 Cited Publications
Cat. No.: HY-113315
CAS No.: 5255-17-4
Purity:  99.93%
3β-Hydroxy-5-cholenoic acid is a steroidal monohydroxy bile acid and serves as a substrate for sulfation reactions. It is applicable to the research of extrahepatic biliary atresia and recurrent intrahepatic cholestasis of pregnancy .
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Cat. No.: HY-136059
CAS No.: 302781-98-2
Target:  

Keap1-Nrf2 Autophagy

Research Areas:  

Cardiovascular Disease Cancer

Desfluoro-ezetimibe is a desfluoro impurity of Ezetimibe. Ezetimibe is a potent, metabolically stable cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator .
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Cat. No.: HY-17376S1
CAS No.: 1093659-89-2
Synonyms: SCH 58235-d4-1
Ezetimibe-d4-1 is deuterium labeled Ezetimibe. Ezetimibe (SCH 58235) is a potent cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator.
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Cat. No.: HY-17376R
CAS No.: 163222-33-1
Synonyms: SCH 58235 (Standard)
Ezetimibe (Standard) is the analytical standard of Ezetimibe. This product is intended for research and analytical applications. Ezetimibe (SCH 58235) is a potent cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator.
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Cat. No.: HY-17376S
CAS No.: 1093659-90-5
Synonyms: SCH 58235-d4
Ezetimibe-d4 (SCH 58235-d4) is the deuterium labeled Ezetimibe (HY-17376). Ezetimibe (SCH 58235) is a potent cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator.
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Cat. No.: HY-17640
CAS No.: 1269181-69-2
Research Areas:  

Metabolic Disease

Nicodicosapent is a fatty acid niacin conjugate that is also an inhibitor of the sterol regulatory element binding protein (SREBP), a key regulator of cholesterol metabolism proteins such as PCSK9, HMG-CoA reductase, ATP citrate lyase, and NPC1L1.
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Cat. No.: HY-RS09475
Research Areas:  

Others

NPC1L1 Human Pre-designed siRNA Set A contains three designed siRNAs for NPC1L1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS17515
Research Areas:  

Others

Npc1l1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Npc1l1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS23972
Research Areas:  

Others

Npc1l1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Npc1l1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P99362
CAS No.: 1092658-06-4
Synonyms: Anti-MUC5AC Reference Antibody (ensituximab); NEO-102

Target:  

Mucin

Research Areas:  

Cancer

Ensituximab (NEO-102; NPC-1C) is a chimeric monoclonal IgG1 antibody targeting a variant of MUC5AC. Ensituximab shows specificity to colorectal and pancreatic cancer .
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Cat. No.: HY-135388
CAS No.: 1376614-99-1
Synonyms: ent-SCH 58235
Target:  

Drug Metabolite

Research Areas:  

Cardiovascular Disease

ent-Ezetimibe (ent-SCH 58235) is the RRS-enantiomer of Ezetimibe. Ezetimibe is a potent cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator .
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Cat. No.: HY-17376S3
CAS No.: 438624-68-1
Synonyms: SCH 58235-13C6
Ezetimibe- 13C6 (SCH 58235- 13C6) is the 13C-labeled Ezetimibe (HY-17376). Ezetimibe (SCH 58235) is a potent cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator.
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Cat. No.: HY-P81911
Synonyms: NPC1 LIKE 1; NPC1L1

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human

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Cat. No.: HY-N18304
CAS No.: 1162664-57-4
Brutieridin (Compound 1) is a flavanone glycoside that can be isolated from the juice of bergamot (Citrus bergamia). Brutieridin reduces the level of NPC1L1 in intestinal epithelial cells. Brutieridin decreases cholesterol uptake by intestinal epithelial cells. Brutieridin reduces HMGR activity. Brutieridin can be used in the research of hypercholesterolemia .
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Cat. No.: HY-160882
CAS No.: 68207-16-9
Target:  

Filovirus

Research Areas:  

Infection

EBOV-IN-7 (compound 26) is an inhibitor of the Ebola virus EBOV with an IC50 of 2.04 μM against EBOV-GP pseudotyped virus (pEBOV). EBOV-IN-7 has inhibitory effects on cancer cells and inhibits the EBOV-GPcl/NPC1 interaction .
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Cat. No.: HY-121315
CAS No.: 1550053-19-4
Target:  

HDAC

Research Areas:  

Metabolic Disease

BRD4097 is an inhibitor of histone deacetylase (HDAC). BRD4097 acts by inhibiting the activity of HDACs, especially HDAC 1,2 and 3, through metal chelation and spatial rejection mechanisms, and this inhibition may help regulate gene expression and alter chromatin structure, thereby affecting a variety of biological processes. BRD4097 is used to study the role of HDAC in cholesterol metabolism and NPC1 diseases .
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