1376614-99-1
1376614-99-1
Chemical Structure
ent-Ezetimibe
Synonym(s): ent-SCH 58235
- CAS No.: 1376614-99-1
- Formula:C24H21F2NO3
- Molecular Weight:409.43
IUPAC Name: (3S,4R)-1-(4-fluorophenyl)-3-((R)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one
InChIKey: OLNTVTPDXPETLC-ZRBLBEILSA-N
SMILES: O=C1N(C2=CC=C(F)C=C2)[C@@H](C3=CC=C(O)C=C3)[C@@H]1CC[C@H](C4=CC=C(F)C=C4)O
Biological Activity: ent-Ezetimibe (ent-SCH 58235) is the RRS-enantiomer of Ezetimibe. Ezetimibe is a potent cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator[1].
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ent-Ezetimibe | ent-Ezetimibe (ent-SCH 58235) is the RRS-enantiomer of Ezetimibe. Ezetimibe is a potent cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator. | |||||||||||||||||||||
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References
Keywords
