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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
Polyadenylic acid
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "Polyadenylic acid" in MCE Product Catalog:
Cat. No.: HY-W416291
CAS No.: 26763-19-9
Synonyms: Poly(A)
Polyadenylic acid potassium (Poly(A)) is a polyribonucleotide. Polyadenylic acid potassium constitutes the 3'-poly(A) tail of eukaryotic mRNAs, governing mRNA maturation, stability, and translation initiation. Polyadenylic acid potassium serves as a target for studying nucleic acid structure-function relationships, with small molecules binding its tail influencing mRNA function and protein production. Polyadenylic acid (potassium) can be used for the research of cancer .
Cat. No.: HY-185721
CAS No.: 25191-14-4
Synonyms: Polyguanylic acid
Target:
Research Areas:
Poly (G) (Polyguanylic acid) is a high-molecular-weight synthetic ribopolynucleotide. In the presence of Na + or K + ions, Poly (G) undergoes time-dependent structural modification, gradually self-assembling from a single strand into large G-quadruplex aggregates. Poly (G) undergoes cooperative secondary structure dissociation under alkaline conditions, but its secondary structure can withstand high temperatures up to 100°C and is resistant to snake venom diesterase at low Na + concentrations. Poly (G) forms stable 1:1 complexes with polycytidylic acid or poly 5-bromocytidylic acid, but does not bind to polyinosinic acid or polyadenylic acid. Poly (G) can be applied to studies on the interactions between drugs and G-rich DNA fragments in electrochemical biosensors .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
