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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
Polycytidylic acid
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "Polycytidylic acid" in MCE Product Catalog:
71
71 Publications Verification
Synonyms: Poly(I:C) sodium
Research Areas:
Polyinosinic-polycytidylic acid (Poly(I:C)) sodium is a synthetic analog of double-stranded RNA and an agonist of toll-like receptor 3 (TLR3) and retinoic acid inducible gene I (RIG-I)-like receptors (RIG-I and MDA5). Polyinosinic-polycytidylic acid sodium can be used as a vaccine adjuvant to enhance innate and adaptive immune responses, and to alter the tumor microenvironment. Polyinosinic-polycytidylic acid sodium can directly trigger cancer cells to undergo apoptosis .
70
Target:
RIG-I-like receptor (RLR) Toll-like Receptor (TLR) PKD HSP Bcl-2 Family Interleukin Related Apoptosis
Research Areas:
Polyinosinic-polycytidylic acid (Poly(I:C)) is a synthetic analog of double-stranded RNA and an agonist of toll-like receptor 3 (TLR3) and retinoic acid inducible gene I (RIG-I)-like receptors (RIG-I and MDA5). Polyinosinic-polycytidylic acid can be used as a vaccine adjuvant to enhance innate and adaptive immune responses, and to alter the tumor microenvironment. Polyinosinic-polycytidylic acid can directly trigger cancer cells to undergo apoptosis .
Cat. No.: HY-134958
CAS No.: 31852-29-6
Synonyms: Poly(I:C) potassium
Target:
Research Areas:
Polyinosinic-polycytidylic acid potassium (Poly(I:C) potassium) is a synthetic analog of double-stranded RNA and an agonist of toll-like receptor 3 (TLR3) and retinoic acid inducible gene I (RIG-I)-like receptors (RIG-I and MDA5). Polyinosinic-polycytidylic acid sodium can be used as a vaccine adjuvant to enhance innate and adaptive immune responses, and to alter the tumor microenvironment. Polyinosinic-polycytidylic acid potassium can directly trigger cancer cells to undergoApoptosis .
Cat. No.: HY-W250152
CAS No.: 26936-40-3
Cat. No.: HY-107202GL
CAS No.: 24939-03-5
Synonyms: Poly(I:C) (GMP Like)
Cat. No.: HY-W682115
CAS No.: 30811-80-4
Synonyms: Polycytidylic acid
Research Areas:
Poly(C) (Polycytidylic acid) is a pleiotropic immunostimulant that specifically binds to TLR3, RIG-I and MDA5 receptors. Poly (C) recruits adaptor proteins to activate downstream signaling pathways and induce the production of type I interferons and inflammatory cytokines. Poly (C) triggers cancer cell apoptosis via the intrinsic or extrinsic caspase pathway, thereby exerting inhibitory effects on tumor growth and metastasis. Poly (C) acts as a vaccine adjuvant to modify the tumor microenvironment, regulate the expression of endothelial adhesion molecules and induce virus-like immune responses. Poly (C) can be applied to research related to melanoma, various solid tumors, hematological malignancies and autoimmune insulin-dependent diabetes mellitus .
Cat. No.: HY-185721
CAS No.: 25191-14-4
Synonyms: Polyguanylic acid
Target:
Research Areas:
Poly (G) (Polyguanylic acid) is a high-molecular-weight synthetic ribopolynucleotide. In the presence of Na + or K + ions, Poly (G) undergoes time-dependent structural modification, gradually self-assembling from a single strand into large G-quadruplex aggregates. Poly (G) undergoes cooperative secondary structure dissociation under alkaline conditions, but its secondary structure can withstand high temperatures up to 100°C and is resistant to snake venom diesterase at low Na + concentrations. Poly (G) forms stable 1:1 complexes with polycytidylic acid or poly 5-bromocytidylic acid, but does not bind to polyinosinic acid or polyadenylic acid. Poly (G) can be applied to studies on the interactions between drugs and G-rich DNA fragments in electrochemical biosensors .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
