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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
25 Results for "
Polymyxin B
" in MedChemExpress (MCE) Product Catalog:
Products (25)
25 Results for "Polymyxin B" in MCE Product Catalog:
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Polymyxin B is an antibiotic. Polymyxin B inhibits Gram-negative infections by binding to the LPS of the bacterial wall with high affinity. Polymyxin B neutralizes the effect of endotoxin. Polymyxin B induces bacterial death by increasing its permeability. Polymyxin B is used in endotoxemia research .
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Infection Microorganisms Antibiotics Mammalian Cell Culture Disease Research Antibacterial Disease Research Fields Other Antibiotics
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3 Cited Publications
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3 Cited Publications
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Infection Microorganisms Antibiotics Disease Research Antibacterial Disease Research Fields Other Antibiotics
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Cat. No.: HY-A0248B
CAS No.: 34503-87-2
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Cat. No.: HY-A0248AS
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Cat. No.: HY-107027
CAS No.: 1338055-88-1
Synonyms: Polymyxin E2 sulfate
Cat. No.: HY-106783R
CAS No.: 86408-36-8
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Cat. No.: HY-106783AR
CAS No.: 2220175-42-6
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Cat. No.: HY-A0248C
CAS No.: 108965-69-1
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Polymyxin B2 Sulfate is a polypeptide antibiotic with particularly potent antibacterial activity against Gram-negative bacteria. Polymyxin B2 Sulfate kills bacteria by binding to lipopolysaccharide molecules on the bacterial cell membrane, disrupting membrane integrity and causing leakage of intracellular contents. Polymyxin B2 Sulfate is used in studies related to Pseudomonas aeruginosa infection and acute enteritis .
Cat. No.: HY-N8280
CAS No.: 129046-69-1
IKD-8344 is a macrocyclic dilactone originally isolated from an actinomycete species and has diverse biological activities, including anticancer, antimicrobial, and anthelmintic properties. It is cytotoxic to L5178Y murine leukemia cells (IC50=0.54 ng/ml).1 IKD-8344 inhibits growth of the mycelial form of C. albicans (MIC=6.25 μg/mL) and potentiates the activity of polymyxin B against the multidrug-resistant pathogenic bacterium B. cenocepacia.
Cat. No.: HY-A0248BR
CAS No.: 34503-87-2
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Cat. No.: HY-174283
CAS No.: 3080635-27-1
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Tri-valent linker-3 is a linker targeting Polymyxin B (PMB) and can be used to synthesize PMB-based drug delivery systems. Polymyxin B carries molecular payloads (e.g., nucleic acid agents) through the linker and binds megalin (a cell surface factor on the surface of target cells) with high affinity, thereby delivering the payload to tissues or cells .
Cat. No.: HY-169187
Antibacterial agent 247 (compund 30b) is a bacterial antagonist that significantly inhibits the formation of Pseudomonas aeruginosa biofilm (IC50=5.8 μM) and multiple virulence phenotypes, and enhances its interaction with Tob Antibacterial activity of combined therapy with ampicillin and polymyxin B .
PA3552-IN-1 (compound 15) is an antibiotic adjuvant that restores sensitivity of MDR P. aeruginosa DK2 strain to Polymyxin B. PA3552-IN-1 can reduce PA3552 expression .
Cat. No.: HY-A0248AS1
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Cat. No.: HY-P1649A
Synonyms: NAB741 TFA
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
