167 Results for "

Protein+C

" in MedChemExpress (MCE) Product Catalog:
Products (167)

167 Results for "Protein+C" in MCE Product Catalog:

13
Withaferin A
Withaferin A
0 Images
13 Publications Verification
Cat. No.: HY-N2065
CAS No.: 5119-48-2
Category:  

other families Withania somnifera Plants Solanaceae Disease Research Fields Inflammation/Immunology Steroids

Target:  

NF-κB Ferroptosis

Withaferin A is a steroidal lactone isolated from Withania somnifera, inhibits NF-kB activation and targets vimentin, with potent antiinflammatory and anticancer activities. Withaferin A is an inhibitor of endothelial protein C receptor (EPCR) shedding.
5
Fluorescein-5-maleimide
Fluorescein-5-maleimide
0 Images
5 Cited Publications
Cat. No.: HY-D0098
CAS No.: 75350-46-8
Synonyms: N-(5-Fluoresceinyl)maleimide
Fluorescein-5-maleimide (N-(5-Fluoresceinyl)maleimide) is a fluorescent dye. Fluorescein-5-maleimide can be used to detect the redox state of thiols in eukaryotic cells. Fluorescein-5-maleimide can label peptides and is used to detect negatively charged nanoparticles. Fluorescein-5-maleimide can also label actin to explore its interaction with cardiac myosin-binding protein C (cMyBP-C), which helps in developing small molecule modulators for heart failure. Fluorescein-5-maleimide can screen mutant proteins that contain cysteine residues. The excitation wavelength of Fluorescein-5-maleimide is 494 nm, and the emission wavelength is 519 nm .
4
Activated Protein C (390-404), human
Activated Protein C (390-404), human
0 Images
4 Cited Publications
Cat. No.: HY-P1918
CAS No.: 146340-20-7
Target:  

APC

Research Areas:  

Cardiovascular Disease

Activated Protein C (390-404), human is a polypeptide fragment of vitamin K-dependent serine protease activated protein C (APC), which inhibits the anticoagulant activity of APC. Activated Protein C (390-404), human inhibits APC-catalyzed inactivation of factor Va .
4
GRO-alpha/CXCL1 Protein, Human (HEK293, His)
GRO-alpha/CXCL1 Protein, Human (HEK293, His)
0 Images
4 Cited Publications
Cat. No.: HY-P70508
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Growth-Regulated Alpha Protein; C-X-C Motif Chemokine 1; GRO-Alpha(1-73); Melanoma Growth Stimulatory Activity; MGSA; Neutrophil-Activating Protein 3; NAP-3; CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
Species:  
Human
Source:  
HEK293
2
Toxin B/TcdB Protein, C. difficile (His)
Toxin B/TcdB Protein, C. difficile (His)
0 Images
2 Cited Publications
Cat. No.: HY-P79219
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Toxin B; Glucosyltransferase TcdB; toxB
Species:  
Others
Source:  
E. coli
2
Serpin A5 Protein, Human (HEK293, His)
Serpin A5 Protein, Human (HEK293, His)
0 Images
2 Cited Publications
Cat. No.: HY-P70975
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Plasma Serine Protease Inhibitor; Acrosomal Serine Protease Inhibitor; Plasminogen Activator Inhibitor 3; PAI-3; PAI3; Protein C Inhibitor; PCI; Serpin A5; SERPINA5; PCI; PLANH3; PROCI
Species:  
Human
Source:  
HEK293
1
Complement C5-IN-1
Complement C5-IN-1
0 Images
1 Cited Publications
Cat. No.: HY-128342
CAS No.: 2365402-67-9
Purity:  99.14%
Target:  

Complement System

Research Areas:  

Inflammation/Immunology

Compound C5-IN-1 (Compound 7) is a selective allosteric inhibitor of complement component protein C5. Compound C5-IN-1 prevents C5 from being cleaved by C5 convertase, inhibits the cleavage of C5 into C5a and C5b, and thus blocks the formation of membrane attack complex (MAC). Compound C5-IN-1 has an IC50 of 0.77 μM and 5 nM in 50% human whole blood and 2% human serum to block MAC deposition induced by zymosan, respectively. Compound C5-IN-1 can be used to study diseases related to complement overactivation, such as paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS) .
1
D-Lys(Z)-Pro-Arg-pNA diacetate
D-Lys(Z)-Pro-Arg-pNA diacetate
0 Images
1 Cited Publications
Cat. No.: HY-P0021A
CAS No.: 108963-70-8
Synonyms: Spectrozyme PCa; Chromozym Pca diacetate
Target:  

Fluorescent Dye

Research Areas:  

Others

D-Lys(Z)-Pro-Arg-pNA diacetate is a chromogenic peptide substrate of activated protein C (APC) .
1
NCL Protein, Human (P.pastoris, His)
NCL Protein, Human (P.pastoris, His)
0 Images
1 Cited Publications
Cat. No.: HY-P71760
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: C23; FLJ45706; MS1116 ; NCL; Nucl; Nucleolin; Protein C23
Species:  
Human
Source:  
P. pastoris
1
SAA4 Protein, Human (His)
SAA4 Protein, Human (His)
0 Images
1 Cited Publications
Cat. No.: HY-P71277
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Serum Amyloid A-4 Protein; Constitutively Expressed Serum Amyloid A Protein; C-SAA; SAA4; CSAA
Species:  
Human
Source:  
E. coli
1
GRO-alpha/CXCL1 Protein, Mouse
GRO-alpha/CXCL1 Protein, Mouse
0 Images
1 Cited Publications
Cat. No.: HY-P7188
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rMuGRO-α/CXCL1; Growth-regulated alpha protein; C-X-C motif chemokine 1; KC; HSF
Species:  
Mouse
Source:  
E. coli
1
Prosurfactant Protein C Antibody (YA6950)
Prosurfactant Protein C Antibody (YA6950)
0 Images
1 Cited Publications
Cat. No.: HY-P87267
Synonyms: BRICD6 antibody; BRICHOS domain containing 6 antibody; PSP C antibody; PSPC antibody; PSPC_HUMAN antibody; Pulmonary surfactant apoprotein 2 antibody; Pulmonary surfactant apoprotein PSP C antibody; pulmonary surfactant apoprotein-2 SP-C antibody; Pulmonary surfactant associated protein C antibody; Pulmonary surfactant associated proteolipid SPL pVal antibody

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, FC, IF-Tissue

Reactivity:  

Human, Mouse, Rat

1
HER3 Protein, Human (HEK293, Fc)
HER3 Protein, Human (HEK293, Fc)
0 Images
1 Cited Publications
Cat. No.: HY-P70322
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuReceptor tyrosine-protein kinase erbB-3/HER3, Fc; Proto-oncogene-like protein c-ErbB-3; Tyrosine kinase-type cell surface receptor HER3; ERBB3; HER3
Species:  
Human
Source:  
HEK293
1
FSP27/CIDEC Antibody
FSP27/CIDEC Antibody
0 Images
1 Cited Publications
Cat. No.: HY-P81068A
Synonyms: Cell Death Activator; Cell death activator CIDE-3; Cell death inducing DFFA like effector protein C; CIDE 3; CIDE C; CIDEC_HUMAN; FLJ20871; FPLD5; FSP27; CIDE-3

Host:  

Rabbit

Application:  

WB, ELISA, IHC-P, IHC-F, FC, ICC/IF

Reactivity:  

Human, Mouse, Rat

1
ETS1/EWSR2 Protein, Human (His)
ETS1/EWSR2 Protein, Human (His)
0 Images
1 Cited Publications
Cat. No.: HY-P70292
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuProtein C-ets-1/ETS1, His; ETS1 Protein; Protein C-ets-1; V-ets Erythroblastosis Virus E26 Oncogene Homolog 1 (Avian); Isoform CRA_a; ETS1; hCG_1732038
Species:  
Human
Source:  
E. coli
1
DDIT3 Antibody (YA3507)
DDIT3 Antibody (YA3507)
0 Images
1 Cited Publications
Cat. No.: HY-P81233
Synonyms: GADD153; CHOP; Growth arrest and DNA damage-inducible 153; C/EBP homologous protein; C/EBP Homology Protein; CEBPZ; CHOP10; DDIT 3; DNA Damage Inducible Transcript 3; GADD 153; Growth Arrest and DNA Damage Inducible Protein 153; Growth arrest and DNA damage inducible protein GADD153; MGC4154; DDIT3_HUMAN.

Host:  

Mouse

Application:  

WB, IHC-P, ICC/IF

Reactivity:  

Human, Mouse, Rat

1
cGAS Protein, Human (His-SUMO)
cGAS Protein, Human (His-SUMO)
0 Images
1 Cited Publications
Cat. No.: HY-P71597
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: C6orf150; cGAMP synthase; cGAS; CGAS_HUMAN; cGMP Synthase; Chromosome 6 open reading frame 150; Cyclic GMP-AMP synthase; h-cGAS; Hypothetical protein LOC115004; Mab 21 domain containing 1; Mab-21 domain-containing protein 1; MB21D1; MGC131892; MGC142166; MGC142168; OTTHUMP00000016743; OTTHUMP00000039330; protein MB21D1; Uncharacterized protein C6orf150
Species:  
Human
Source:  
E. coli
Ravulizumab
Ravulizumab
0 Images
Cat. No.: HY-P99365
CAS No.: 1803171-55-2
Synonyms: ALXN1210

Target:  

Complement System

Research Areas:  

Metabolic Disease

Ravulizumab (ALXN1210) is a humanized monoclonal antibody that specifically binds with high affinity to the human complement protein C5. Ravulizumab can be used for the research of paroxysmal nocturnal hemoglobinuria, atypical hemolytic uremic syndrome, and myasthenia gravis .
N-Acetylserine
N-Acetylserine
0 Images
Cat. No.: HY-134222A
CAS No.: 16354-58-8
Purity:  ≥98.0%
Synonyms: N-Acetyl-L-serine
Category:  

Natural Products Other Diseases Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite Complement System

N-Acetylserine (N-Acetyl-L-serine) is a complement pathway modulator targeting activated third complement protein (C3b) and an amino-terminal residue (an N-terminal acetylation modification group). N-Acetylserine reacts with the exposed thioester group of C3b via its hydroxyl group, thereby blocking the covalent binding of glycerol to this thioester group. N-Acetylserine widely exists in soluble proteins of mammalian cells (accounting for approximately 80% of such proteins). N-Acetylserine has a blocking property that prevents direct Edman sequencing of proteins; deblocking is achievable through trifluoroacetic acid-catalyzed N→O acetyl migration followed by β-elimination. N-Acetylserine is suitable for sequencing of proteins with N-terminal acetylserine modification .
c-Myc inhibitor 6
c-Myc inhibitor 6
0 Images
Cat. No.: HY-148836
CAS No.: 2768765-58-6
Purity:  98.04%
Target:  

c-Myc

Research Areas:  

Infection Cardiovascular Disease Cancer

c-Myc inhibitor 6 (compound A102) is a c-Myc inhibitor. c-Myc inhibitor 6 decreases cancer cell viability and degrades c-Myc protein. c-Myc inhibitor 6 can be used for the research of c-Myc imbalance, such as cancer, cardiovascular diseases, and viral infection .
Assay Types