33 Results for "

Protein kinase C substrate

" in MedChemExpress (MCE) Product Catalog:
Products (33)

33 Results for "Protein kinase C substrate" in MCE Product Catalog:

Cat. No.: HY-P3764
CAS No.: 105802-82-2
Target:  

PKC

Research Areas:  

Others

Protein kinase C substrate is a substrate of Protein kinase C, can be used to detect protein. Protein kinase C is a key regulatory element in signal transduction and exerts its effects by catalysing specific substrate phosphorylation .
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2
2 Cited Publications
Cat. No.: HY-P1821
CAS No.: 126768-94-3
Synonyms: MHP4-14
Target:  

PKC

Research Areas:  

Neurological Disease

Myelin Basic Protein (MHP4-14), a synthetic peptide comprising residues 4-14 of myelin basic protein, is a very selective PKC substrate (Km=7 μM). Myelin Basic Protein is not phosphorylated by cyclic AMP-dependent protein kinase, casein kinases I and II, Ca 2+/calmodulin-dependent protein kinase II, or phosphorylase kinase, and can be routinely used for the assay of protein kinase C with low background in the crude tissue extracts .
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2
2 Cited Publications
Cat. No.: HY-P3815
CAS No.: 132176-35-3
Target:  

Casein Kinase

Research Areas:  

Others

Casein Kinase 2 Substrate Peptide is a common CK2 substrate peptide. Casein Kinase 2 Substrate Peptide is synthesized with its C-terminus conjugated to 5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid (EDANS). Casein Kinase 2 Substrate Peptide can be used for protein kinase CK2 activity determination .
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2
2 Cited Publications
Cat. No.: HY-P1821A
Synonyms: MHP4-14 TFA
Target:  

PKC

Research Areas:  

Neurological Disease

Myelin Basic Protein (MHP4-14) TFA, a synthetic peptide comprising residues 4-14 of myelin basic protein, is a very selective PKC substrate (Km=7 μM). Myelin Basic Protein TFA is not phosphorylated by cyclic AMP-dependent protein kinase, casein kinases I and II, Ca 2+/calmodulin-dependent protein kinase II, or phosphorylase kinase, and can be routinely used for the assay of protein kinase C with low background in the crude tissue extracts .
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1
1 Cited Publications
Cat. No.: HY-P1746
CAS No.: 121545-65-1
Synonyms: PKC (19-31)
Target:  

PKC

Research Areas:  

Inflammation/Immunology

Protein Kinase C (19-31), a peptide inhibitor of protein kinase C (PKC), derived from the pseudo-substrate regulatory domain of PKCa (residues 19-31), is used as protein kinase C substrate peptide for testing the protein kinase C activity .
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Cat. No.: HY-159805
CAS No.: 2813260-27-2
Target:  

CDK

Research Areas:  

Cancer

CDK2-IN-31 is a CCNE1:CDK2 complex inhibitor with an IC50 of 0.13 μM. CDK2-IN-31 binds to a cryptic allosteric pocket at the CCNE1:CDK2 interface, inducing structural rearrangements of the CDK2 A-loop that disrupt the kinase's active conformation and interfere with substrate binding. CDK2-IN-31 inhibits phosphorylation of retinoblastoma protein 1 (RB1) in CCNE1-dependent ovarian cancer cells. CDK2-IN-31 impairs coenrichment of protein PRC1 with CCNE1-N112C:CDK2 complexes. CDK2-IN-31 can be used for the research of ovarian cancer .
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Cat. No.: HY-W011297
CAS No.: 2566-89-4
Synonyms: Arachidonic acid methyl ester
Target:  

PKC

Research Areas:  

Metabolic Disease

Methyl arachidonate is a protein kinase C activator and also an orally active substrate that undergoes esterase-mediated hydrolysis. Methyl arachidonate indirectly activates protein kinase C via eicosanoid metabolites generated through the arachidonic acid metabolic pathway, exerting effects via cyclooxygenase products at low concentrations and via lipoxygenase products at high concentrations. Methyl arachidonate can be used in studies related to lipodystrophy .
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Cat. No.: HY-P10471A
Synonyms: MARCKS-ED TFA
Target:  

MARCKS PKC

Research Areas:  

Others

MPSD TFA (MARCKS-ED TFA) is the TFA salt form of MPSD (HY-P10471). MPSD TFA is a 25-amino acid peptide based on the effector domain sequence of the intracellular membrane protein myristoylated alanine-rich C-kinase substrate (MARCKS). MPSD TFA can sense membrane curvature and recognize phosphatidylserine. MPSD TFA can be utilized as biological probe to study membrane shape and lipid composition .
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Cat. No.: HY-P2673
CAS No.: 121284-21-7
Synonyms: KRTLRR
Target:  

EGFR

Research Areas:  

Others

Lys-Arg-Thr-Leu-Arg-Arg (KRTLRR) is a hexapeptide. Lys-Arg-Thr-Leu-Arg-Arg is a substrate of protein kinase C from EGF receptor. Lys-Arg-Thr-Leu-Arg-Arg can be used to determine the activity of protein kinase C .
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Cat. No.: HY-P10471E
Synonyms: MARCKS-ED control peptide TFA
Target:  

MARCKS

Research Areas:  

Others

MPSD control peptide (MARCKS-ED control peptide) TFA is the control peptide of MPSD (HY-P10471). MPSD (MARCKS-ED) is a 25-amino acid peptide based on the effector domain sequence of the intracellular membrane protein myristoylated alanine-rich C-kinase substrate (MARCKS) .
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Cat. No.: HY-13856
CAS No.: 1410101-89-1
Purity:  98.09%
Target:  

PDK-1

Research Areas:  

Cancer

(R)-PS210, the R enantiomer of PS210 (compound 4h-eutomer), is a substrate-selective allosteric activator of PDK1 with an AC50 value of 1.8 μM. (R)-PS210 targets to the PIF-binding pocket of?PDK1. PIF: The protein kinase C-related kinase 2 (PRK2)-interacting fragment .
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Cat. No.: HY-121197
CAS No.: 63590-19-2
Synonyms: Ophiocordin; Azepinostatin
Target:  

MARCKS PKA PKC

Balanol (Ophiocordin; Azepinostatin) is a potent and ATP competitive PKC/PKA inhibitor against human PKC isozymes α, β-I, β-II, γ, δ, ε, η (IC50s=4-9 nM) and ζ (IC50=150 nM). Balanol also blocks the phosphorylation of cyclic AMP response element-binding protein (CREB) and myristoylated alanine-rich C kinase substrate (MARCKS). Balanol can be isolated from the fungus Verticillium balanoides .
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Cat. No.: HY-P1088
CAS No.: 136795-05-6
Target:  

PKC

Research Areas:  

Others

[Ser25] Protein Kinase C (19-31) is a substrate of protein kinase C (PKC) (Km: 0.3 μM). [Ser25] Protein Kinase C (19-31) is derived from the pseudo-substrate regulatory domain of PKCα (19-31) with a Serine at position 25 replacing the wild-type Alanine .
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Cat. No.: HY-P3892
CAS No.: 309247-48-1
Target:  

PKC

Research Areas:  

Inflammation/Immunology

Protein Kinase C (19-35) Peptide is the PKC pseudosubstrate inhibitor/region. Protein Kinase C (19-35) Peptide possibly blocks the substrate-binding site in its kinase domain, makes the cytoplasmic form of PKC inactive .
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Cat. No.: HY-P3743
CAS No.: 165190-42-1
Target:  

Src Peptides

Research Areas:  

Others

p60c-src Substrate is an efficient and specific substrate for p60c-src protein tyrosine kinase (PTK). p60c-src Substrate can be used to synthesize chimeric branched peptides .
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Cat. No.: HY-P1803
CAS No.: 120253-69-2
Synonyms: PKCε; PRKCE ; Peptide Epsilon
Protein Kinase C Peptide Substrate is targeted to a specific cellular compartment in a manner dependent on second messengers and on specific adapter proteins in response to extracellular signals that activate G-protein-coupled receptors, tyrosine kinase receptors, or tyrosine kinase-coupled receptors. Protein Kinase C Peptide Substrate then regulates various physiological functions including the activation of nervous, endocrine, exocrine, inflammatory, and immune systems .
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Cat. No.: HY-P3741
CAS No.: 105802-84-4
Target:  

PKC

Research Areas:  

Neurological Disease

[Ala9,10, Lys11,12] Glycogen Synthase (1-12) is a selective substrate for phosphorylation by protein kinase C (PKC). [Ala9,10, Lys11,12] Glycogen Synthase (1-12) can be used to determine the activity of protein kinase C .
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Cat. No.: HY-P3940
CAS No.: 138250-62-1
Target:  

PKC

Research Areas:  

Others

Ac-MBP (4-14) Peptide is an acetylated MBP (4-14) peptide. MBP (4-14) Peptide is a very selective (protein kinase C) PKC substrate. Ac-MBP (4-14) Peptide can be used for PKC assay in extracts without prior purification to eliminate interfering protein kinases or phosphatases .
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Cat. No.: HY-P10471
CAS No.: 134248-85-4
Synonyms: MARCKS-ED
Target:  

MARCKS PKC

Research Areas:  

Others

MPSD (MARCKS-ED) is a 25-amino acid peptide based on the effector domain sequence of the intracellular membrane protein myristoylated alanine-rich C-kinase substrate (MARCKS). MPSD can sense membrane curvature and recognize phosphatidylserine. MPSD can be utilized as biological probe to study membrane shape and lipid composition .
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Cat. No.: HY-P10471D
CAS No.: 190711-66-1
Synonyms: MARCKS-ED control peptide
Target:  

MARCKS PKC

Research Areas:  

Others

MPSD control peptide (MARCKS-ED control peptide) is a control peptide for MPSD peptide (HY-P10471). MPSD (MARCKS-ED) is a 25-amino acid peptide based on the effector domain sequence of the intracellular membrane protein myristoylated alanine-rich C-kinase substrate (MARCKS). MPSD can sense membrane curvature and recognize phosphatidylserine. MPSD can be utilized as biological probe to study membrane shape and lipid composition .
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