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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
ROS receptor kinase
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "ROS receptor kinase" in MCE Product Catalog:
S116836, a potent, orally active BCR-ABL tyrosine kinase inhibitor, blocks both wild-type as well as T315I Bcr-Abl. S116836 arrests the cells in the G0/G1 phase of cell cycle, induces apoptosis, increases ROS production, and decreases GSH production in BaF3/WT and BaF3/T315I cells. S116836 also inhibits SRC, LYN, HCK, LCK and BLK, and receptor tyrosine kinases such as FLT3, TIE2, KIT, PDGFR-β. Antitumor activies . S116836 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Target:
Research Areas:
ROS kinases-IN-2 is a ROS kinase inhibitor. ROS kinases-IN-2 can be used for research on stomach cancer, liver cancer and colorectal cancer .
Cat. No.: HY-P702714
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: ROS1; Proto-Oncogene C-ROS-1; ROS Proto-Oncogene 1, receptor TyROSine kinase; V-ROS UR2 Sarcoma Virus Oncogene Homolog 1 (Avian); MCF3; ROS Proto-Oncogene 1 , receptor TyROSine kinase; ROS; Transmembrane TyROSine-Specific Protein kinase; C-ROS-1; receptor
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P87054
Synonyms: c ROS 1 antibody; c ROS antibody; c ROS oncogene 1 receptor tyROSine kinase antibody; c ROS receptor tyROSine kinase antibody; c ROS1 antibody; MCF 3 antibody; MCF3 antibody; Oncogene ROS antibody; OTTHUMP00000017814 antibody; OTTHUMP00000017815 antibody; c ROS 1 antibody; c ROS antibody; c ROS oncogene 1 receptor tyROSine kinase antibody; c ROS receptor tyROSine kinase antibody; c ROS1 antibody; MCF 3 antibody; MCF3 antibody; Oncogene ROS antibody; OTTHUMP00000017814 antibody; OTTHUMP00000017815 antibody; OTTHUMP00000040389 antibody; Proto oncogene c ROS 1 protein antibody; Proto oncogene c ROS antibody; Proto oncogene tyROSine protein kinase ROS antibody; Proto oncogene tyROSine protein kinase ROS precursor antibody; Proto-oncogene c-ROS-1 antibody; Proto-oncogene tyROSine-protein kinase ROS antibody; receptor tyROSine kinase c ROS oncogene 1 antibody; ROS 1 antibody; ROS 1C antibody; ROS antibody; ROS proto oncogene 1 , receptor tyROSine kinase antibody; ROS_HUMAN antibody; ROS1 antibody; ROS1C antibody; Transmembrane tyROSine specific protein kinase antibody; v ROS avian UR2 sarcoma virus oncogene homolog 1 antibody; v ROS UR2 sarcoma virus oncogene homolog 1 antibody;
Cat. No.: HY-P705880
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ROS1; Proto-Oncogene C-ROS-1; ROS Proto-Oncogene 1, receptor TyROSine kinase; V-ROS UR2 Sarcoma Virus Oncogene Homolog 1 (Avian); MCF3; ROS Proto-Oncogene 1 , receptor TyROSine kinase; ROS; Transmembrane TyROSine-Specific Protein kinase; C-ROS-1; receptor
Species:
Human
Source:
sf9 insect cells
Cat. No.: HY-P706095
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: ROS1; Proto-Oncogene C-ROS-1; ROS Proto-Oncogene 1, receptor TyROSine kinase; V-ROS UR2 Sarcoma Virus Oncogene Homolog 1 (Avian); MCF3; ROS Proto-Oncogene 1 , receptor TyROSine kinase; ROS; Transmembrane TyROSine-Specific Protein kinase; C-ROS-1; receptor
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P706096
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: ROS1; Proto-Oncogene C-ROS-1; ROS Proto-Oncogene 1, receptor TyROSine kinase; V-ROS UR2 Sarcoma Virus Oncogene Homolog 1 (Avian); MCF3; ROS Proto-Oncogene 1 , receptor TyROSine kinase; ROS; Transmembrane TyROSine-Specific Protein kinase; C-ROS-1; receptor
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-117123
CAS No.: 37206-04-5
Category:
Cat. No.: HY-180197
Target:
Research Areas:
PICK1 PDZ-IN-1 (Compound 6b) is a selective and brain-penetrant protein interacting with C kinase 1 (PICK1) PDZ domain inhibitor with a Ki of 27.73 μM. PICK1 PDZ-IN-1 can competitively inhibit the interaction between PICK1 and the GluA2 subunit of AMPA receptors. PICK1 PDZ-IN-1 can increase the survival rate of HT22 cells and primary cortical neuron cells induced by glutamate and inhibit ROS production. PICK1 PDZ-IN-1 exhibits neuroprotective effect and reduces the area of cerebral infarction. PICK1 PDZ-IN-1 can be used for the research of ischemic stroke .
Cat. No.: HY-L075
3,042 compounds
Lung cancer is a major global health problem, as it is the leading cause of cancer-related deaths worldwide. Lung cancer is divided into two categories: small cell lung cancer and non-small cell lung cancer (NSCLC). Non-small cell lung cancer accounts for about 85 percent of lung cancers.
As with all cancers, lung cancer may be treated with surgery, chemotherapy, radiation therapy, targeted therapy, immunotherapy or a combination thereof. Targeted therapy is one of the most exciting developments in lung cancer medicine, especially for NSCLC. Extensive genomic characterization of NSCLC has led to the identification of molecular subtypes of NSCLC that are oncogene addicted and exquisitely sensitive to targeted therapies. These include activating mutations in epidermal growth factor receptor (EGFR) and BRAF or echinoderm microtubule-associated protein-like 4 (EML4)-anaplastic lymphoma kinase (ALK) fusions and ROS1 receptor tyrosine kinase fusions. These are important targets for target therapy.
MCE offers a unique collection of 3,042 compounds with identified and potential anti-lung cancer activity. These compounds target lung cancer’s major targets and signaling pathways. MCE anti-lung cancer compound library is a useful tool for anti-lung cancer drugs screening and other related research.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
