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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
24 Results for "
Sarcosine
" in MedChemExpress (MCE) Product Catalog:
Products (24)
24 Results for "Sarcosine" in MCE Product Catalog:
3
3 Cited Publications
Synonyms: N-Methylglycine; Sarcosin
Category:
Human Gut Microbiota Metabolites Microorganisms Immune System Disorder Disease markers Endocrine diseases Amino acids Endogenous metabolite Disease Research Fields Cancer
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Creatininase, Microorganism (Creatinine amidohydrolase; CAH), namely creatinine amidohydrolase, from Pseudomonas putida, is a homohexameric enzyme commonly used in biochemical research. Creatininase acts on carbon-nitrogen bonds other than peptide bonds, and can catalyze the hydrolysis of creatinine to creatine, which can then be metabolized by creatinase to urea and sarcosine .
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Sarcosine oxidase, Bacillus (SAO) can catalyze the oxidative demethylation of sarcosine to generate glycine, H2O2, 5,10-CH2-tetrahydrofolate, which are often used in biochemical reactions .
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1 Cited Publications
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Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
N-Propargylglycine is a brain-penetrant and orally active PRODH inhibitor. N-Propargylglycine covalently modifies enzyme-bound FAD and active site lysine, causing enzyme structural distortion, protein decay, and irreversible inhibition of proline and 4-hydroxyproline catabolism. N-Propargylglycine induces UPRmt, upregulates mitochondrial chaperones and YME1L1, enhances mitochondrial proteostasis, blocks astrocytic L-proline consumption, and abolishes L-proline’s ATP-maintaining and viability-protective effects. N-Propargylglycine stimulates neural processes, increases brain proline, hydroxyproline, and sarcosine levels, partially normalizes Huntington’s disease whole brain transcriptomes. N-Propargylglycine reduces hyperoxaluria, prevents calcium oxalate stone formation, reduces kidney tubular damage, and restores weight and survival in Grhpr knockout mice. N-Propargylglycine can be used for the research of breast cancer, neurodegenerative disorders, Huntington’s disease, and primary hyperoxaluria type 2 .
Cat. No.: HY-P4198
CAS No.: 2375600-56-7
Synonyms: Fmoc-Sar10
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Cat. No.: HY-N16040
CAS No.: 2936622-30-7
Synonyms: N-Methylglycine-d3; Sarcosin-d3
Cat. No.: HY-P2893
CAS No.: 37340-58-2
Synonyms: Creatine amidohydrolase
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Creatinase, Actinobacteria (Creatine amidohydrolase) is a hydrolase that catalyzes the hydrolysis of creatine into sarcosine and urea, and plays an important role in the enzymatic determination of creatinine concentration .
Cat. No.: HY-P2893A
CAS No.: 37340-58-2
Synonyms: Creatine amidinohydrolase
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Creatinase (Recombinant) is a hydrolase responsible for catalyzing the hydrolysis of creatine (HY-W010388) into sarcosine (HY-101037) and urea (HY-Y0271). Creatinase (Recombinant) can be used in conjunction with creatinine deiminase (HY-P2838) and sarcosine oxidase (HY-P2861) in an enzyme cascade reaction to measure creatinine (HY-B0504) levels in blood and urine. Creatinase (Recombinant) is the rate-limiting enzyme in this enzymatic cascade, and the enzymatic quantification of creatinine is an important method for evaluating kidney function .
Cat. No.: HY-164166
CAS No.: 2749824-37-9
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Cat. No.: HY-101037R
CAS No.: 107-97-1
Synonyms: N-Methylglycine (Standard); Sarcosin (Standard)
Cat. No.: HY-W1116287
CAS No.: 2313534-28-8
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Cat. No.: HY-101037S
Purity: ≥99.0%
Synonyms: N-Methylglycine-15N; Sarcosin-15N
Cat. No.: HY-Y1144
CAS No.: 52605-49-9
Synonyms: N-[(Ethoxycarbonyl)methyl]-N-methylamine hydrochloride; Sacrosine ethyl ester hydrochloride
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Cat. No.: HY-W748519
CAS No.: 2806125-84-6
Synonyms: N-Methylglycine-13C3; Sarcosin-13C3
Cat. No.: HY-W188178
CAS No.: 13256-22-9
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N-Nitrososarcosine is a nitrosation product of Sarcosine (HY-101037) and can be found in cured meat products. N-Nitrososarcosine (225 mg/kg) induces the formation of metastatic liver carcinomas in mice .
Cat. No.: HY-172288
CAS No.: 2847775-93-1
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N-TETAMINE-pSar45 is a polysarcosine (pSar) derivative featuring an N-tetamine head group and a 45-mer polysarcosine tail. Sarcosine is an amino acid derivated that is being developed as an alternative to PEG for in vivo applications due to its biodegradability and highly reduced antigenicity. pSar-lipid derivatives such as this may be applied in the development of lipid nanoparticles.
Cat. No.: HY-P2861A
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Sarcosine Oxidase, E.coli catalyzes the demethylation of sarcosine to glycine.
Cat. No.: HY-E70955
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Sarcosine Dehydrogenase, Pseudomonas sp. (EC 1.5.99.1) is a mitochondrial enzyme that catalyzes the chemical reaction N-demethylation of sarcosine to give glycine. Sarcosine dehydrogenase, Pseudomonas sp. (EC 1.5.99.1) is an oxidoreductase that acts on the CH-NH group of donor molecules and other acceptor molecules.
Cat. No.: HY-P702177
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Monomeric Sarcosine oxidase; EC:1.5.3.1; MSOX; soxA
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
