Sarcosine-15N
Based on 1 Customer Validation
Sarcosine-15N is the 15N-labeled Sarcosine. Sarcosine (N-Methylglycine), an endogenous amino acid, is a competitive glycine transporter type I (GlyT1) inhibitor and N-methyl-D-aspartate (NMDA) receptor co-agonist. Sarcosine increases the glycine concentration, resulting in an indirect potentiation of the NMDA receptor. Sarcosine is commonly used for the research of schizophrenia.
For research use only. We do not sell to patients.
- Purity: 99.92%
- Formula: C3H715NO2
- Molecular Weight:90.09
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Storage:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
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GlyT1 |
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 107-97-1
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Appearance Solid
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Molecular Weight 90.09
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Formula C3H715NO2
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Color White to off-white
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SMILES
O=C(C[15NH]C)O
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Synonyms
N-Methylglycine-15N; Sarcosin-15N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
H2O : 100 mg/mL (1110.00 mM; Need ultrasonic)
DMSO : 1 mg/mL (11.10 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / H2O | 1 mM | 11.1000 mL | 55.5001 mL | 111.0001 mL | 277.5003 mL |
| 5 mM | 2.2200 mL | 11.1000 mL | 22.2000 mL | 55.5001 mL | |
| 10 mM | 1.1100 mL | 5.5500 mL | 11.1000 mL | 27.7500 mL | |
| H2O | 15 mM | 0.7400 mL | 3.7000 mL | 7.4000 mL | 18.5000 mL |
| 20 mM | 0.5550 mL | 2.7750 mL | 5.5500 mL | 13.8750 mL | |
| 25 mM | 0.4440 mL | 2.2200 mL | 4.4400 mL | 11.1000 mL | |
| 30 mM | 0.3700 mL | 1.8500 mL | 3.7000 mL | 9.2500 mL | |
| 40 mM | 0.2775 mL | 1.3875 mL | 2.7750 mL | 6.9375 mL | |
| 50 mM | 0.2220 mL | 1.1100 mL | 2.2200 mL | 5.5500 mL | |
| 60 mM | 0.1850 mL | 0.9250 mL | 1.8500 mL | 4.6250 mL | |
| 80 mM | 0.1388 mL | 0.6938 mL | 1.3875 mL | 3.4688 mL | |
| 100 mM | 0.1110 mL | 0.5550 mL | 1.1100 mL | 2.7750 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Sarcosine-15N Related Classifications
HY-101037S Related Classifications
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