107-97-1
107-97-1
Chemical Structure
Sarcosine
Synonym(s): N-Methylglycine; Sarcosin
- CAS No.: 107-97-1
- Formula:C3H7NO2
- Molecular Weight:89.09
IUPAC Name: methylglycine
InChIKey: FSYKKLYZXJSNPZ-UHFFFAOYSA-N
SMILES: O=C(O)CNC
Biological Activity: Sarcosine (N-Methylglycine), an endogenous amino acid, is a competitive glycine transporter type I (GlyT1) inhibitor and N-methyl-D-aspartate (NMDA) receptor co-agonist. Sarcosine increases the glycine concentration, resulting in an indirect potentiation of the NMDA receptor. Sarcosine is commonly used for the research of schizophrenia[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Sarcosine | 98.0% | Sarcosine (N-Methylglycine), an endogenous amino acid, is a competitive glycine transporter type I (GlyT1) inhibitor and N-methyl-D-aspartate (NMDA) receptor co-agonist. Sarcosine increases the glycine concentration, resulting in an indirect potentiation of the NMDA receptor. Sarcosine is commonly used for the research of schizophrenia. | ||||||||||||||||||||
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Sarcosine (Standard) | 99.93% | Sarcosine (Standard) is the analytical standard of Sarcosine. This product is intended for research and analytical applications. Sarcosine (N-Methylglycine), an endogenous amino acid, is a competitive glycine transporter type I (GlyT1) inhibitor and N-methyl-D-aspartate (NMDA) receptor co-agonist. Sarcosine increases the glycine concentration, resulting in an indirect potentiation of the NMDA receptor. Sarcosine is commonly used for the research of schizophrenia. | ||||||||||||||||||||
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Sarcosine-13C3 | Sarcosine-13C3 (N-Methylglycine-13C3; Sarcosin-13C3) is the 13C-labeled Sarcosine (HY-101037). Sarcosine (N-Methylglycine), an endogenous amino acid, is a competitive glycine transporter type I (GlyT1) inhibitor and N-methyl-D-aspartate (NMDA) receptor co-agonist. Sarcosine increases the glycine concentration, resulting in an indirect potentiation of the NMDA receptor. Sarcosine is commonly used for the research of schizophrenia. | |||||||||||||||||||||
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Sarcosine-d3 | 99.85% | Sarcosine-d3 is the deuterium labeled Sarcosine. Sarcosine (N-Methylglycine), an endogenous amino acid, is a competitive glycine transporter type I (GlyT1) inhibitor and N-methyl-D-aspartate (NMDA) receptor co-agonist. Sarcosine increases the glycine concentration, resulting in an indirect potentiation of the NMDA receptor. Sarcosine is commonly used for the research of schizophrenia. | ||||||||||||||||||||
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Sarcosine-15N | 99.92% | Sarcosine-15N is the 15N-labeled Sarcosine. Sarcosine (N-Methylglycine), an endogenous amino acid, is a competitive glycine transporter type I (GlyT1) inhibitor and N-methyl-D-aspartate (NMDA) receptor co-agonist. Sarcosine increases the glycine concentration, resulting in an indirect potentiation of the NMDA receptor. Sarcosine is commonly used for the research of schizophrenia. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.96
HY-W012791S2-(Methylamino)acetic acid-d3 hydrochloride -
Similarity Score 0.95
HY-W0127912-(Methylamino)acetic acid hydrochloride -
Similarity Score 0.86
HY-W0767053-(Methylamino)propanoic acid -
Similarity Score 0.82
HY-W141879N-Ethylglycine -
Similarity Score 0.81
HY-W751082H-N-Me-Ala-OH-13C,d3 -
Similarity Score 0.80
HY-W704091α-Amino-β-methylaminopropionic acid-d3 hydrochloride -
Similarity Score 0.79
HY-W001158S1N,N-Dimethylglycine-d3 hydrochloride -
Similarity Score 0.78
HY-W779386N-Acetylglycine-13C2, 15N -
Similarity Score 0.78
HY-Y0069N-Acetylglycine -
Explore the MedChemAI to find more analogs
References
- [1]. Katarzyna Socała, et al. Effects of sarcosine, a glycine transporter type 1 inhibitor, in two mouse seizure models. Pharmacol Rep. Mar-Apr 2010;62(2):392-7. [Content Brief]
- [2]. Mei-Yi Lee, et al. Effects of sarcosine and N, N-dimethylglycine on NMDA receptor-mediated excitatory field potentials. J Biomed Sci. 2017; 24: 18. [Content Brief]
